Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739802 | 0.89 | NPC1 (0.32) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL4739132 | 0.88 | KDM4E (0.40) | RAB9ANPC1RIPK1KDM4E | |
| SCHEMBL4734073 | 0.86 | CHIA (0.33) | RAB9ANPC1LMNACCNA2CDK2 | |
| SCHEMBL4738609 | 0.86 | DHODH (0.36) | RAB9ANPC1LMNAKMT2AKDM4E | |
| SCHEMBL4739290 | 0.84 | PDE10A (0.33) | RAB9ANPC1 | |
| SCHEMBL4737853 | 0.83 | PTGES (0.38) | — | |
| SCHEMBL4782354 | 0.83 | KDM4E (0.32) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL4737025 | 0.83 | HPGD (0.40) | LMNAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5109671 | 0.82 | RORC (0.34) | RAB9ANPC1CNR1CNR2KMT2A | |
| SCHEMBL4235330 | 0.82 | HTR4 (0.34) | RAB9ANPC1CNR1CNR2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | claimed |