Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 9/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728771 | 0.98 | MMP1 (0.34) | ATP4AATP4BMMP1ERBB2MINK1 | |
| SCHEMBL4784127 | 0.89 | PPARD (0.33) | TRPV3GRM2PPARD | |
| SCHEMBL4782623 | 0.89 | PPARD (0.34) | ATP4AATP4BTRPV3GRM2PPARD | |
| SCHEMBL4780494 | 0.84 | ERBB2 (0.46) | ATP4AATP4BERBB2MINK1TRPV3 | |
| SCHEMBL4732040 | 0.84 | TRPV3 (0.35) | ATP4AATP4BERBB2MINK1TRPV3 | |
| SCHEMBL4728357 | 0.81 | ERBB2 (0.37) | ATP4AATP4BERBB2MINK1TRPV3 | |
| SCHEMBL4730718 | 0.81 | GRM2 (0.34) | ATP4AATP4BERBB2MINK1TRPV3 | |
| SCHEMBL4728989 | 0.80 | TRPV3 (0.34) | ATP4AATP4BTRPV3GRM2PPARD | |
| SCHEMBL4726101 | 0.77 | TRPV3 (0.32) | ATP4AATP4BERBB2MINK1TRPV3 | |
| SCHEMBL4730015 | 0.77 | PPARD (0.34) | ATP4AATP4BGRM2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008034579-A1 | 2-HETEROCYCLYL-5-PHENOXYMETHYLPYRIDINE DERIVATIVES AS ANTICANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-27 | — | — | WO | disclosed |