Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 7/20 | 0.43 |
| ▸ | PTGES | O14684 | 5/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784907 | 0.86 | RHEB (0.46) | TTRRORCPTGESNPC1RAB9A | |
| SCHEMBL4786153 | 0.86 | EIF4E (0.50) | TTRRORCPTGESEIF4EDHODH | |
| SCHEMBL3795491 | 0.86 | PTGES (0.43) | TTRPTGESEIF4EDHODHJAK2 | |
| SCHEMBL29662800 | 0.84 | PTGES (0.43) | PTGESJAK2 | |
| SCHEMBL4786450 | 0.81 | HDAC1 (0.46) | NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL3796320 | 0.80 | PTGES (0.49) | PTGESPIM1PIM3JAK2 | |
| SCHEMBL4783861 | 0.80 | NPC1 (0.54) | EIF4ENPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL3792228 | 0.80 | PTGES (0.39) | TTRPTGESEIF4EPIM1PIM3 | |
| SCHEMBL13075946 | 0.80 | DEGS1 (0.46) | PTGESNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2360979 | 0.79 | PTGES (0.43) | TTRPTGESEIF4EDHODHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |