Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783219 | 0.86 | TTR (0.55) | PTGESKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3797090 | 0.84 | RHEB (0.41) | RHEBPTGESALDH1A1KDM4EMAPK14 | |
| SCHEMBL4799427 | 0.81 | IDO1 (0.47) | RHEBPTGESALDH1A1KDM4ENPC1 | |
| SCHEMBL3790901 | 0.81 | PTGES (0.39) | RHEBPTGESALDH1A1MAPK14NPC1 | |
| SCHEMBL3798547 | 0.81 | PTGES (0.39) | RHEBPTGESALDH1A1MAPK14NPC1 | |
| SCHEMBL29662800 | 0.81 | PTGES (0.43) | PTGESMAPK14 | |
| SCHEMBL4786450 | 0.79 | HDAC1 (0.46) | KDM4ENPC1RAB9ALMNAPKM | |
| SCHEMBL4785278 | 0.78 | PTGES (0.52) | RHEBPTGESALDH1A1KDM4EMAPK14 | |
| SCHEMBL4786153 | 0.77 | EIF4E (0.50) | PTGESTTRRORC | |
| SCHEMBL3795491 | 0.77 | PTGES (0.43) | PTGESTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |