Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 4/20 | 0.50 |
| ▸ | DHODH | Q02127 | 6/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783219 | 0.86 | TTR (0.55) | EIF4EDHODHRORCPTGESTTR | |
| SCHEMBL3795491 | 0.84 | PTGES (0.43) | EIF4EDHODHPTGESTTRKMO | |
| SCHEMBL29662800 | 0.80 | PTGES (0.43) | PTGES | |
| SCHEMBL3796320 | 0.78 | PTGES (0.49) | PTGES | |
| SCHEMBL2360979 | 0.77 | PTGES (0.43) | EIF4EDHODHPTGESTTRKMO | |
| SCHEMBL4784907 | 0.77 | RHEB (0.46) | RORCPTGESTTR | |
| SCHEMBL13076230 | 0.77 | PTGES (0.43) | PTGES | |
| SCHEMBL13075541 | 0.77 | KDM4E (0.43) | PTGESKMO | |
| SCHEMBL3796002 | 0.76 | PTGES (0.43) | PTGES | |
| SCHEMBL13075530 | 0.76 | SMN1; SMN2 (0.43) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |