Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 16/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782077 | 0.91 | NPC1 (0.44) | HTR6DRD2HTR2ANPC1BCHE | |
| SCHEMBL4780971 | 0.86 | BRD4 (0.45) | BRD4HTR6NPC1BCHE | |
| SCHEMBL4785064 | 0.85 | TSHR (0.48) | HTR6 | |
| SCHEMBL4782045 | 0.84 | HTR6 (0.45) | BRD4HTR6DRD2HTR2AHTR1A | |
| SCHEMBL4784929 | 0.81 | ALDH1A1 (0.45) | HTR6 | |
| SCHEMBL4782126 | 0.81 | KEAP1 (0.44) | BRD4HTR6DRD2HTR2ANPC1 | |
| SCHEMBL4780287 | 0.79 | ALDH1A1 (0.48) | HTR6DRD2HTR2A | |
| SCHEMBL4783496 | 0.79 | NPC1 (0.46) | HTR6NPC1 | |
| SCHEMBL4782615 | 0.78 | NPC1 (0.46) | HTR6DRD2HTR2ANPC1 | |
| SCHEMBL4781621 | 0.78 | HTR6 (0.41) | HTR6DRD2HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |