Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 2/20 | 0.48 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2257145 | 0.81 | NSD3 (0.53) | PLATNSD3HTR2CTDP1HTR2A | |
| Bicarbonate SCHEMBL5261153 | 0.78 | NSD3 (0.50) | PLATNSD3HTR2CCYP1A2TDP1 | |
| SCHEMBL3959958 | 0.76 | HTR2C (0.48) | PLATHTR2CGNRHRCYP1A2TDP1 | |
| Hydrochloric Acid SCHEMBL3250146 | 0.76 | HTR2C (0.48) | PLATHTR2CGNRHRCYP1A2TDP1 | |
| SCHEMBL4783576 | 0.75 | CALCRL (0.40) | ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL17803273 | 0.75 | CTSS (0.51) | PLATNSD3TYMPTDP1ALDH1A1 | |
| SCHEMBL14161419 | 0.72 | LMNA (0.38) | TDP1LMNAHSD17B10 | |
| SCHEMBL4734858 | 0.72 | PLAT (0.45) | PLATHTR2CGNRHRCYP1A2TDP1 | |
| SCHEMBL14161352 | 0.72 | ADORA3 (0.42) | ABL1FYNALDH1A1 | |
| SCHEMBL15137228 | 0.71 | L3MBTL1 (0.48) | TYMPALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070014-A2 | BIARYL KETONE-SUBSTITUTED PIPERIDINES | NEUROGEN CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008070014-A2 | BIARYL KETONE-SUBSTITUTED PIPERIDINES | NEUROGEN CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008060568-A2 | AMIDE-SUBSTITUTED ARYL PIPERIDINES | NEUROGEN CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |