Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 6/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783079 | 0.81 | AKR1C3 (0.45) | ALDH1A1PTGES | |
| SCHEMBL4785325 | 0.81 | TDP1 (0.51) | ALDH1A1LMNAPKMSMN1; SMN2HTR6 | |
| SCHEMBL4785309 | 0.81 | HTR6 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2HTR6 | |
| SCHEMBL4784743 | 0.80 | HTR6 (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2HTR6 | |
| SCHEMBL4782361 | 0.79 | TBXAS1 (0.46) | TBXA2RSMN1; SMN2 | |
| SCHEMBL4783275 | 0.78 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2HTR6 | |
| SCHEMBL4784746 | 0.78 | LMNA (0.39) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4783430 | 0.78 | CNR2 (0.48) | ALDH1A1PKMHTR6 | |
| SCHEMBL4781323 | 0.76 | HTR6 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2HTR6 | |
| SCHEMBL4784894 | 0.76 | KMT2A (0.44) | ALDH1A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |