Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786450 | 0.91 | HDAC1 (0.46) | HDAC1MEN1KMT2APRSS12HDAC2 | |
| SCHEMBL4786423 | 0.85 | MEN1 (0.47) | HDAC1MEN1KMT2AHDAC2HDAC3 | |
| SCHEMBL4783219 | 0.78 | TTR (0.55) | KDM4EPTGES | |
| SCHEMBL4786495 | 0.78 | PTGES (0.47) | HDAC1PRSS12HDAC2HDAC3PTGES | |
| SCHEMBL3800201 | 0.77 | PTGES (0.43) | HDAC1MEN1KMT2AHDAC2HDAC3 | |
| SCHEMBL4784907 | 0.76 | RHEB (0.46) | MEN1KMT2AKDM4EPTGES | |
| SCHEMBL13075946 | 0.76 | DEGS1 (0.46) | MEN1KMT2AHDAC6PTGES | |
| SCHEMBL13075516 | 0.76 | NPC1 (0.46) | MEN1KMT2APRSS12KDM4EPTGES | |
| SCHEMBL4784998 | 0.75 | PTGES (0.45) | HDAC1PRSS12HDAC2HDAC3PTGES | |
| SCHEMBL4847730 | 0.74 | PTGES (0.45) | HDAC1PRSS12HDAC2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |