Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160491 | 0.91 | ACLY (0.50) | MAPTLMNARECQLALDH1A1MEN1 | |
| SCHEMBL4787528 | 0.90 | ALDH1A1 (0.47) | MAPTLMNARECQLNPSR1ALDH1A1 | |
| SCHEMBL4746863 | 0.86 | MAPT (0.45) | MAPTALDH1A1KMT2ATDP1POLB | |
| SCHEMBL4746166 | 0.79 | TSHR (0.43) | MAPTLMNARECQLNPSR1ALDH1A1 | |
| SCHEMBL8154008 | 0.79 | MAPT (0.49) | MAPTLMNARECQLALDH1A1MEN1 | |
| SCHEMBL4788634 | 0.79 | SMN1; SMN2 (0.48) | MAPTLMNARECQLALDH1A1MEN1 | |
| SCHEMBL4787536 | 0.78 | ALDH1A1 (0.55) | MAPTLMNARECQLALDH1A1MEN1 | |
| SCHEMBL4786988 | 0.77 | ALDH1A1 (0.46) | MAPTLMNARECQLALDH1A1MEN1 | |
| SCHEMBL4742206 | 0.76 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5292057 | 0.76 | MEN1 (0.47) | MAPTLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |