Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788418 | 0.89 | THRB (0.47) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL4787431 | 0.83 | IDO1 (0.47) | KMT2AMEN1IDO1TP53TDP1 | |
| SCHEMBL4805415 | 0.80 | KMT2A (0.49) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5243352 | 0.78 | KMT2A (0.43) | KMT2AMEN1IDO1TDP1ALDH1A1 | |
| SCHEMBL4746102 | 0.78 | ACLY (0.44) | KMT2AMEN1TP53ALDH1A1HTT | |
| SCHEMBL4786255 | 0.78 | L3MBTL1 (0.48) | KMT2AMEN1TP53ALDH1A1TSHR | |
| SCHEMBL4746866 | 0.75 | HTT (0.48) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL4787833 | 0.75 | AKR1C3 (0.40) | KMT2AMEN1IDO1TDP1ALDH1A1 | |
| SCHEMBL5244144 | 0.75 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL5292057 | 0.73 | MEN1 (0.47) | KMT2AMEN1TDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |