Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789292 | 0.90 | NAMPT (0.38) | CTSKKEAP1CTSLCTSBCTSS | |
| SCHEMBL4789865 | 0.86 | KEAP1 (0.51) | CTSKKEAP1CTSLCTSBCTSS | |
| SCHEMBL4788689 | 0.77 | PDE4B (0.46) | DPP4DPP8DPP7 | |
| SCHEMBL4790305 | 0.76 | USP30 (0.41) | CTSKKEAP1CTSLCTSBCTSS | |
| SCHEMBL4789901 | 0.74 | HDAC6 (0.38) | CTSKKEAP1CTSLCTSBCTSS | |
| SCHEMBL4787930 | 0.73 | CTSK (0.69) | CTSKCTSBCTSS | |
| SCHEMBL3264278 | 0.70 | CTSK (0.48) | CTSKCTSBCTSS | |
| SCHEMBL4789696 | 0.70 | DPP8 (0.38) | CTSKKEAP1CTSLCTSBCTSS | |
| SCHEMBL4584329 | 0.69 | HRH3 (0.40) | L3MBTL1 | |
| SCHEMBL4573371 | 0.69 | HSD11B1 (0.48) | DPP4DPP8KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001128-A1 | 1,2-CYCL0HEXANE DICARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |