Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192840 | 0.79 | MAOA (0.40) | ACHETDP1TOP2AMAOAMAOB | |
| SCHEMBL1756151 | 0.72 | PARP1 (0.47) | ACHETYMSMAOAMAOBKDM4E | |
| SCHEMBL12583810 | 0.70 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL17298630 | 0.68 | — | — | |
| SCHEMBL15358756 | 0.67 | ALOX15 (0.32) | TDP1ALOX15 | |
| SCHEMBL7187432 | 0.66 | MAOA (0.40) | ACHETOP2AMAOAMAOBKDM4E | |
| SCHEMBL2087097 | 0.66 | TDP1 (0.60) | TDP1ALOX15TYMSMAOAMAOB | |
| SCHEMBL31548711 | 0.66 | TDP1 (0.60) | TDP1ALOX15TYMSMAOAMAOB | |
| SCHEMBL29539686 | 0.65 | ALOX15 (0.52) | ACHETDP1ALOX15TYMSMEN1 | |
| SCHEMBL166198 | 0.65 | ALOX15 (0.52) | ACHETDP1ALOX15TYMSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883919-B2 | Reinforced polymetric materials, methods of manufacture thereof and articles comprising the same | THE UNIVERSITY OF MASSACHUSETTS (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130253140-A1 | REINFORCED POLYMETRIC MATERIALS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | THE UNIVERSITY OF MASSACHUSETTS (US) | 2013-09-26 | — | — | US | disclosed |
| US-8455096-B2 | Reinforced polymeric materials, methods of manufacture thereof and articles comprising the same | THE UNIVERSITY OF MASSACHUSETTS (US) | 2013-06-04 | — | — | US | disclosed |
| US-20080268239-A1 | REINFORCED POLYMERIC MATERIALS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | THE UNIVERSITY OF MASSACHUSETTS (US) | 2008-10-30 | — | — | US | disclosed |
| WO-2008121798-A1 | REINFORCED POLYMERIC MATERIALS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | UNIVERSITY OF MASSACHUSETTS (US) | 2008-10-09 | — | — | WO | disclosed |