Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 1.00 |
| ▸ | DHFR | P00374 | 3/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941435 | 1.00 | ADORA2A (1.00) | ADORA2ADHFRPIK3CGPDPK1GDA | |
| Hydrochloric Acid SCHEMBL6448601 | 0.98 | ADORA2A (0.95) | ADORA2ADHFRPIK3CGPDPK1GDA | |
| Bromide SCHEMBL64823 | 0.98 | ADORA2A (0.95) | ADORA2ADHFRPIK3CGPDPK1GDA | |
| Bromide SCHEMBL29767030 | 0.98 | ADORA2A (0.95) | ADORA2ADHFRPIK3CGPDPK1GDA | |
| SCHEMBL30432637 | 0.83 | ADORA2A (0.70) | ADORA2ADHFRPIK3CGPDPK1GDA | |
| SCHEMBL9014935 | 0.81 | ADORA2A (0.66) | ADORA2ADHFRPIK3CGPIK3CAPIK3CB | |
| SCHEMBL23889475 | 0.77 | ADORA2A (0.63) | ADORA2ADHFRKDM4EALDH1A1LMNA | |
| SCHEMBL19876656 | 0.77 | ADORA2A (0.63) | ADORA2ADHFR | |
| SCHEMBL13186957 | 0.77 | ADORA2A (0.63) | ADORA2ADHFR | |
| SCHEMBL22055303 | 0.77 | ADORA2A (0.63) | ADORA2ADHFRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3125864-A1 | SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS | Vasopharm GmbH (DE) | 2017-02-08 | — | — | EP | claimed |
| WO-2015150294-A1 | SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS | VASOPHARM GMBH (DE) | 2015-10-08 | — | — | WO | claimed |
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | claimed |
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | claimed |
| US-7135550-B2 | Compositions and methods for isolating ligand binding polypeptides for a user-specified ligand, and for isolating small molecule ligands for a user-specified target polypeptide using an improved class of hybrid ligand compounds | GPC BIOTECH INC. (US) | 2006-11-14 | — | — | US | claimed |
| EP-1364212-A4 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2005-05-04 | — | — | EP | claimed |
| CN-1543465-A | Novel heterocyclic compounds as selective bacterial DHFR inhibitors and uses thereof | ��������ҽѧ����˾ | 2004-11-03 | — | — | CN | claimed |
| US-20040043388-A1 | Three hybrid assay system | GPC BIOTECH AG (DE) | 2004-03-04 | — | — | US | claimed |
| EP-1364212-A2 | THREE HYBRID ASSAY SYSTEM | GPC Biotech AG (DE) | 2003-11-26 | — | — | EP | claimed |
| US-20030165873-A1 | For isolating ligand binding polypeptides; fusion proteins; drug screening; kits; surface plasmon resonance | GPC BIOTECH AG (DE) | 2003-09-04 | — | — | US | claimed |
| WO-2002070662-A2 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2002-09-12 | — | — | WO | claimed |
| US-20260048056-A1 | SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS | VASOPHARM GMBH (DE) | 2026-02-19 | — | — | US | disclosed |
| CN-120988935-A | Selective medium and method for screening or separating aeromonas | 上海市农业科学院 | 2025-11-21 | — | — | CN | disclosed |
| US-12458644-B2 | Process for preparing solutions comprising biopterin derivatives | VASOPHARM GMBH (DE) | 2025-11-04 | — | — | US | disclosed |
| US-20250114466-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2025-04-10 | — | — | US | disclosed |
| US-4374987-A | FROM 2,4,5,6-TETRAMINOPYRIMIDINE SULFATE, 1,1,3-TRIBROMOACETONE AND A ZINC P-AMINOBENZOYLGLUTAMATE | AMERICAN CYANAMID COMPANY (US) | 1983-02-22 | — | — | US | disclosed |
| US-4369319-A | TREATMENT OF LEUKEMIA AND TUMORS | DEGRAW JR JOSEPH I (US) | 1983-01-18 | — | — | US | disclosed |
| US-4080325-A | REACTING TETRAAMINOPYRIMIDINE HYDROCHLORIDE WITH DIHYDROXYACETONE, MULTISTAGE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE | 1978-03-21 | — | — | US | disclosed |
| US-4079056-A | REACTING 2,4-DIAMINO-6-PTERIDINE-METHANOL-HBR WITH TRIPHENYLPHOSPHINE DIBROMIDE OR PHOSPHORUS TRIBROMIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1978-03-14 | — | — | US | disclosed |
| US-4077957-A | INTERMEDIATE FOR METHOTREXATE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250114466-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | DHFR, FOLR1, MTHFD2 | ADORA2A 3382/4885DHFR 1/4885PIK3CG 4353/4885 |
| US-20030165873-A1 | For isolating ligand binding polypeptides; fusion proteins; drug screening; kits; surface plasmon resonance | MST1R, PLAUR, SPR | ADORA2A 4224/4885DHFR 1302/4885PIK3CG 3729/4885 |
| US-12458644-B2 | Process for preparing solutions comprising biopterin derivatives | PPIP5K2, THPO, SLC20A2 | ADORA2A 1216/4885DHFR 1727/4885PIK3CG 284/4885 |
| US-20260048056-A1 | SOLID PHARMACEUTICAL COMPOSITIONS COMPRISING BIOPTERIN DERIVATIVES AND USES OF SUCH COMPOSITIONS | CYP11B2, CYP11B1, HSD11B2 | ADORA2A 2179/4885DHFR 3142/4885PIK3CG 1086/4885 |
| US-20040043388-A1 | Three hybrid assay system | ACKR3, KLK3, TIMCC | ADORA2A 4045/4885DHFR 1425/4885PIK3CG 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.