Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790547 | 0.91 | ALDH1A1 (0.42) | ALDH1A1TSHRADRA1AADRA1DADRA1B | |
| SCHEMBL4789955 | 0.90 | TSHR (0.42) | ALDH1A1TSHRADRA1AADRA1DADRA1B | |
| SCHEMBL4789432 | 0.87 | ADRA1D (0.42) | ALDH1A1TSHRADRA1AADRA1DADRA1B | |
| SCHEMBL4789858 | 0.81 | ADRA1A (0.47) | ALDH1A1TSHRADRA1AADRA1DADRA1B | |
| SCHEMBL4788471 | 0.80 | CHRM3 (0.37) | ALDH1A1TSHRTAAR1TRPM8CHRM2 | |
| SCHEMBL4789352 | 0.79 | TSHR (0.47) | TSHRMEN1KMT2AKDM4EDRD2 | |
| SCHEMBL4788059 | 0.78 | CHRM3 (0.37) | ALDH1A1TSHRTAAR1TRPM8CHRM3 | |
| SCHEMBL4789383 | 0.78 | CHRM3 (0.36) | ALDH1A1TSHRMEN1KMT2ATAAR1 | |
| SCHEMBL4789529 | 0.78 | ADRA1A (0.41) | ALDH1A1TSHRADRA1AADRA1DADRA1B | |
| SCHEMBL4787715 | 0.77 | CYP1A2 (0.38) | ALDH1A1TSHRKMT2ATAAR1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |