Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789381 | 0.90 | ALDH1A1 (0.44) | TSHRALDH1A1ADRA1AADRA1DADRA1B | |
| SCHEMBL4789352 | 0.90 | TSHR (0.47) | TSHRKDM4EMEN1KMT2ALMNA | |
| SCHEMBL4789529 | 0.88 | ADRA1A (0.41) | TSHRALDH1A1ADRA1AADRA1DADRA1B | |
| SCHEMBL4788488 | 0.86 | CHRM3 (0.40) | TSHRALDH1A1ADRA1AADRA1DADRA1B | |
| SCHEMBL4755411 | 0.85 | CHRM2 (0.46) | ADRA1ACHRM2CHRM1CHRM3ADRB2 | |
| SCHEMBL4790547 | 0.83 | ALDH1A1 (0.42) | TSHRALDH1A1ADRA1AADRA1DADRA1B | |
| SCHEMBL4789694 | 0.82 | CHRM3 (0.48) | TSHRALDH1A1ADRA1AADRA1DADRA1B | |
| SCHEMBL4788570 | 0.80 | CHRM3 (0.38) | TSHRALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL4789539 | 0.78 | CHRM3 (0.41) | TSHRMEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL4789432 | 0.78 | ADRA1D (0.42) | TSHRALDH1A1ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |