Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789955 | 0.90 | TSHR (0.42) | TSHRSIGMAR1LMNAKDM4EDRD2 | |
| SCHEMBL4757519 | 0.83 | KCNA3 (0.54) | DRD2DRD3 | |
| SCHEMBL4790247 | 0.81 | SIGMAR1 (0.48) | TSHRSIGMAR1LMNAMCHR1FAAH | |
| SCHEMBL4789539 | 0.80 | CHRM3 (0.41) | TSHRMEN1KMT2A | |
| SCHEMBL4789381 | 0.79 | ALDH1A1 (0.44) | TSHRKDM4EDRD2MEN1KMT2A | |
| SCHEMBL4788570 | 0.78 | CHRM3 (0.38) | TSHR | |
| SCHEMBL4789529 | 0.78 | ADRA1A (0.41) | TSHRLMNAKDM4EDRD2DRD3 | |
| SCHEMBL4788488 | 0.77 | CHRM3 (0.40) | TSHRLMNAKDM4EDRD2MEN1 | |
| SCHEMBL4755411 | 0.75 | CHRM2 (0.46) | DRD2DRD3 | |
| SCHEMBL5818614 | 0.74 | ALDH1A1 (0.51) | TSHRSIGMAR1TRPV6MCHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |