Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559647 | 0.73 | SIGMAR1 (0.46) | USP2KDM4ETSHRMEN1KMT2A | |
| SCHEMBL9548562 | 0.72 | MEN1 (0.56) | ALDH1A1MAPTUSP2METAP2DPP7 | |
| SCHEMBL14602764 | 0.72 | MEN1 (0.56) | ALDH1A1MAPTUSP2METAP2DPP7 | |
| SCHEMBL1681188 | 0.72 | HTT (0.67) | ALDH1A1GAAHTTMEN1KMT2A | |
| SCHEMBL8815679 | 0.70 | MEN1 (0.55) | DPP7EPHX1MEN1KMT2AMMP8 | |
| SCHEMBL4732560 | 0.69 | HTT (0.69) | ALDH1A1GAAHTTKDM4EMEN1 | |
| SCHEMBL2875261 | 0.69 | ALDH1A1 (0.72) | ALDH1A1GAAHTTKDM4ETSHR | |
| SCHEMBL8303682 | 0.69 | L3MBTL1 (0.54) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL7404199 | 0.69 | ALDH1A2 (0.50) | ALDH1A1DPP7EPHX1MMP8 | |
| SCHEMBL9157273 | 0.69 | DPP7 (0.48) | ALDH1A1MAPTUSP2METAP2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |