Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 16/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788570 | 0.90 | CHRM3 (0.38) | CHRM3ACHECHRM2CHRM1TSHR | |
| SCHEMBL4788471 | 0.80 | CHRM3 (0.37) | CHRM3CHRM2CHRM1TSHR | |
| SCHEMBL4789352 | 0.80 | TSHR (0.47) | MEN1KMT2ATSHR | |
| SCHEMBL4789936 | 0.79 | CHRM3 (0.33) | CHRM3ACHECHRM2CHRM1MEN1 | |
| SCHEMBL4789955 | 0.78 | TSHR (0.42) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL4789383 | 0.74 | CHRM3 (0.36) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL4788059 | 0.74 | CHRM3 (0.37) | CHRM3TSHR | |
| SCHEMBL4789010 | 0.74 | ALDH1A1 (0.35) | CHRM3ACHECHRM2CHRM1TSHR | |
| SCHEMBL4789923 | 0.73 | CHRM3 (0.39) | CHRM3CHRM2CHRM1TSHR | |
| SCHEMBL4790311 | 0.72 | CCR1 (0.36) | ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |