Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788351 | 0.91 | ALDH1A1 (0.34) | CHRM3ALDH1A1TSHRNPSR1ACHE | |
| SCHEMBL4788570 | 0.89 | CHRM3 (0.38) | CHRM3ALDH1A1TSHRACHETAAR1 | |
| SCHEMBL4789529 | 0.83 | ADRA1A (0.41) | CHRM3ALDH1A1TSHRHTR2AHTR2B | |
| SCHEMBL4790238 | 0.81 | ALDH1A1 (0.35) | CHRM3ALDH1A1TSHRNPSR1ACHE | |
| SCHEMBL4788471 | 0.79 | CHRM3 (0.37) | CHRM3ALDH1A1TSHRHTR2AHTR2C | |
| SCHEMBL4789539 | 0.79 | CHRM3 (0.41) | CHRM3TSHRACHEMEN1KMT2A | |
| SCHEMBL4789676 | 0.79 | POLB (0.32) | ALDH1A1TSHRNPSR1HTR2AHTR2C | |
| SCHEMBL4757548 | 0.77 | CHRM3 (0.46) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4789432 | 0.77 | ADRA1D (0.42) | ALDH1A1TSHRKDM4EMAPK1MEN1 | |
| SCHEMBL4789873 | 0.76 | CHRM3 (0.39) | CHRM3ALDH1A1TSHRACHEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |