Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513546 | 0.86 | LMNA (0.33) | POLBALDH1A1MAPK1TP53MAPT | |
| SCHEMBL4792173 | 0.85 | TP53 (0.34) | POLBALDH1A1MAPK1TP53MAPT | |
| SCHEMBL4794357 | 0.84 | PIK3CB (0.33) | POLBALDH1A1PIK3CBTP53MAPT | |
| SCHEMBL4792910 | 0.82 | TLR8 (0.37) | TP53MAPTLMNAGRM5DCPS | |
| SCHEMBL1775006 | 0.82 | MAPT (0.36) | ALDH1A1MAPK1TP53MAPTLMNA | |
| SCHEMBL4702114 | 0.82 | ACHE (0.38) | POLBALDH1A1TP53MAPTMTOR | |
| SCHEMBL4707903 | 0.80 | TLR7 (0.37) | ALDH1A1TP53MAPTLMNA | |
| SCHEMBL1776124 | 0.79 | GRM5 (0.36) | ALDH1A1TP53MAPTLMNAGRM5 | |
| SCHEMBL2241078 | 0.79 | ALDH1A1 (0.35) | POLBALDH1A1MAPK1TP53MAPT | |
| SCHEMBL2243546 | 0.77 | DHFR (0.33) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831221-A4 | SUBSTITUTED CHIRAL FUSED 1,2 IMIDAZO 4,5-C RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1831221-A2 | SUBSTITUTED CHIRAL FUSED 1,2 IMIDAZO 4,5-C RING COMPOUNDS | 3M Innovative Properties Company (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006083440-A2 | SUBSTITUTED CHIRAL FUSED [1,2]IMIDAZO[4,5-C] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |