Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 10/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4792620 | 0.85 | CDK9 (0.39) | CDK9PRPS1 | |
| SCHEMBL4790266 | 0.79 | CDK9 (0.42) | CDK9HRH3PRPS1FLT3 | |
| SCHEMBL4792357 | 0.74 | PRPS1 (0.40) | CDK9PRPS1 | |
| SCHEMBL4793189 | 0.70 | HRH3 (0.40) | CDK9HRH3PRPS1FLT3 | |
| SCHEMBL4944385 | 0.70 | HRH3 (0.71) | HRH3 | |
| SCHEMBL2883568 | 0.69 | HRH3 (0.76) | HRH3 | |
| SCHEMBL2881996 | 0.69 | HRH3 (0.76) | HRH3 | |
| SCHEMBL4014376 | 0.69 | HRH3 (0.49) | HRH3 | |
| SCHEMBL3672590 | 0.68 | HRH3 (0.79) | HRH3 | |
| SCHEMBL3672593 | 0.68 | HRH3 (0.79) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994022-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | claimed |
| WO-2007108936-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-09-27 | — | — | WO | claimed |
| EP-1994022-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007108936-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-09-27 | — | — | WO | disclosed |