Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL1030825 | 0.80 | — | — | |
| Ethylenediamine SCHEMBL28256231 | 0.78 | — | — | |
| Ethylenediamine SCHEMBL4426035 | 0.78 | NFKB1 (0.44) | — | |
| Piperazine SCHEMBL5946683 | 0.76 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL2882663 | 0.76 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL14739784 | 0.76 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL3905641 | 0.73 | HIF1A (0.50) | — | |
| Ethylenediamine SCHEMBL3898035 | 0.72 | — | — | |
| Ethylenediamine SCHEMBL5088799 | 0.72 | MAPT (0.46) | — | |
| Ethylenediamine SCHEMBL28255110 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257683-A1 | VEHICLE HARD SURFACE COMPOSITION CONTAINING GRAPHENE | ILLINOIS TOOL WORKS INC. (US) | 2023-08-17 | — | — | US | claimed |
| EP-4166637-A1 | VEHICLE HARD SURFACE COMPOSITION CONTAINING GRAPHENE | Illinois Tool Works, Inc. (US) | 2023-04-19 | — | — | EP | claimed |
| US-20200368675-A1 | LOW ENERGY CONSUMPTION ANHYDROUS CO2 PHASE CHANGE ABSORPTION AGENT, AND REGENERATION METHOD AND APPLICATION THEREOF | TIANGONG UNIVERSITY (CN) | 2020-11-26 | — | — | US | claimed |
| US-9663409-B2 | Liquid phosphite fertilizer | THE ANDERSONS INC. (US) | 2017-05-30 | — | — | US | claimed |
| US-20150007626-A1 | LIQUID PHOSPHITE FERTILIZER | THE ANDERSONS INC | 2015-01-08 | — | — | US | claimed |
| US-20100233264-A1 | TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2010-09-16 | — | — | US | claimed |
| WO-2008032338-A2 | IMPROVED PROCESS FOR THE PREPARATION OF EZETIMIBE AND ITS INTERMEDIATES | SATYANARAYANA REDDY MANNE (IN) | 2008-03-20 | — | — | WO | claimed |
| US-6838566-B2 | Salts of HMG-CoA reductase inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2005-01-04 | — | — | US | claimed |
| EP-1114021-B1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2004-07-14 | — | — | EP | claimed |
| US-6726899-B2 | FOR DISINFECTING A CALCIFIED TISSUE STRUCTURE, DENTISTRY | ADVANTAGE DENTAL PRODUCTS, INC. | 2004-04-27 | — | — | US | claimed |
| US-20030120086-A1 | New salts of HMG-CoA reductase inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2003-06-26 | — | — | US | claimed |
| US-6583295-B1 | Amine salts of such as lovastatin, pravastatin, simvastatin, mevastatin or atorvastatin | LEK PHARMACEUTICALS D.D. (SI) | 2003-06-24 | — | — | US | claimed |
| US-6572374-B2 | Dental bonding formulation complexing calcified deposits associated with a dentinal tubule opening | ADVANTAGE DENTAL PRODUCTS, INC. | 2003-06-03 | — | — | US | claimed |
| US-20030072781-A1 | Calcified tissue facing preparation containing antimicrobial agent | ADVANTAGE DENTAL PRODUCTS, INC. | 2003-04-17 | — | — | US | claimed |
| US-20020009693-A1 | Dental restoration solution for root and dentinal tubule treatment and a method for use thereof | ADVANTAGE DENTAL PRODUCTS, INC. | 2002-01-24 | — | — | US | claimed |
| EP-1114021-A1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2001-07-11 | — | — | EP | claimed |
| WO-2000017150-A1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | LEK PHARMACEUTICAL AND CHEMICAL COMPANY D.D. (DE) | 2000-03-30 | — | — | WO | claimed |
| US-4885156-A | COMPLEXING ALKALI OR ALKALINE EARTH METAL SALT OF AMINOCARBOXYLIC ACID WITH HEAVY METAL; ANTIALLERGEN | Suomen Calcusan Oy-Finska Calcussan AB (FI) | 1989-12-05 | — | — | US | claimed |
| EP-0098157-B1 | ABSORPTION PROCESS FOR PRODUCING OXYGEN AND NITROGEN AND SOLUTIONS THEREFOR | BEND RESEARCH, INC. (US) | 1988-05-04 | — | — | EP | claimed |
| US-4604442-A | Organopolysiloxane-polyamide block polymers and method for making | GENERAL ELECTRIC COMPANY (US) | 1986-08-05 | — | — | US | claimed |