Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL2882663 | 0.95 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL14739784 | 0.95 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL5946683 | 0.95 | HIF1A (0.55) | — | |
| Piperazine SCHEMBL3905641 | 0.91 | HIF1A (0.50) | — | |
| Piperazine SCHEMBL3905644 | 0.88 | HIF1A (0.46) | — | |
| Pyrrolidine SCHEMBL2814299 | 0.88 | — | — | |
| Piperidine SCHEMBL4128881 | 0.84 | ALDH1A1 (0.64) | — | |
| Ethylenediamine SCHEMBL479509 | 0.80 | — | — | |
| Monoethanolamine SCHEMBL27274629 | 0.79 | — | — | |
| Piperazine SCHEMBL9562685 | 0.79 | NFKB1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120548-A | Polyethyleneimine ammonium salt ionic liquid and preparation method and application thereof | 上海庚彩新材料科技有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-116041190-A | Polyethylene polyamine type ammonium salt ionic liquid and preparation method and application thereof | 上海庚彩新材料科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| EP-3208246-B1 | NEEDLE FELT OF MINERAL WOOL AND NEEDLING ADDITIVE, USE OF THE NEEDLING ADDITIVE TO NEEDLE MINERAL WOOL | SAINT GOBAIN ISOVER (FR) | 2019-11-13 | — | — | EP | claimed |
| EP-1833901-A1 | VULCANIZABLE HALOGENATED ELASTOMER COMPOSITIONS | Dow Gloval Technologies Inc. (US) | 2007-09-19 | — | — | EP | claimed |
| WO-2006069191-A1 | VULCANIZABLE HALOGENATED ELASTOMER COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-06-29 | — | — | WO | claimed |
| US-12637616-B2 | Etching solution for selectively removing silicon-germanium alloy from a silicon-germanium/ silicon stack during manufacture of a semiconductor device | VERSUM MATERIALS US, LLC (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4739514-A1 | RUBBER MIXTURES CONTAINING POLYETHYLENEIMINE AND AT LEAST ONE PROCESSING AID CONTAINING AT LEAST ONE FATTY ACID | LANXESS Deutschland GmbH (DE) | 2026-05-13 | — | — | EP | disclosed |
| US-20260055430-A1 | LENTIVIRUS WITH ALTERED INTEGRASE ACTIVITY | FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) | 2026-02-26 | — | — | US | disclosed |
| US-12466918-B2 | Mixtures containing an aminically crosslinkable rubber and polyethyleneimine | LANXESS DEUTSCHLAND GMBH (DE) | 2025-11-11 | — | — | US | disclosed |
| US-20250270572-A1 | GENE EXPRESSION ELEMENTS AND SYSTEMS AND USE THEREOF | GENENEER LTD. (IL) | 2025-08-28 | — | — | US | disclosed |
| US-12390795-B2 | Preparation of supported metal nanoparticles using polyamine for three-way catalysis application | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2025-08-19 | — | — | US | disclosed |
| US-20250127912-A1 | COMPOSITIONS FOR DELIVERY OF POLYNUCLEOTIDES | MIRECULE, INC. | 2025-04-24 | — | — | US | disclosed |
| US-6187227-B1 | INHIBITING THE METAL CORROSION AGAINST ACID GAS BY ADDING A STABILIZER SELECT FROM A THIACROWN ETHER COMPOUND, AN ADDITIONAL POLYMER MODIFIED BY A THIACROWN ETHER COMPOUND OR A CYCLIC POLYTHIOETHERS | BETZDEARBORN | 2001-02-13 | — | — | US | disclosed |
| US-6147225-A | Thiacrown ether compound | BETZDEARBORN INC. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0727391-B1 | Polymeric dithiocarbamic acid salt and method of use | BETZ EUROP INC (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999062898-A2 | THIACROWN ETHER COMPOUND | BETZDEARBORN INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0962551-A1 | Thiacrown ether compound corrosion inhibitors for alkanolamine units. | Betzdearborn Europe, Inc. (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5594096-A | PRECIPITATION OF CONTAMINANTS FROM AQUEOUS SOLUTIONS; WASTEWATER TREATMENT | BETZDEARBORN INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0727391-A2 | Polymeric dithiocarbamic acid salt and method of use | BETZ EUROPE, INC. (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5523002-A | COMPLEXING AGENTS FOR METAL CONTAMINANTS IN AQUEOUS SOLUTIONS | BETZ LABORATORIES, INC. (US) | 1996-06-04 | — | — | US | disclosed |