Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801084 | 0.88 | PTGS1 (0.42) | PTGS1PTGS2XDHALOX5SKP2 | |
| SCHEMBL4799196 | 0.84 | PTGS1 (0.38) | PTGS1PTGS2XDHALOX5SKP2 | |
| Carbamic Acid SCHEMBL4795442 | 0.80 | PTGS1 (0.40) | PTGS1PTGS2XDHALOX5BACE1 | |
| SCHEMBL4799147 | 0.79 | ALDH1A1 (0.46) | XDHCYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL4799682 | 0.79 | PTGS1 (0.50) | PTGS1PTGS2XDHALOX5BACE1 | |
| SCHEMBL14178710 | 0.72 | MEN1 (0.40) | PTGS1PTGS2XDHCYP3A4CYP1A2 | |
| Carbamic Acid SCHEMBL4800912 | 0.72 | ALDH1A1 (0.50) | XDHPTPN1CYP3A4ALDH1A1HPGD | |
| SCHEMBL14178711 | 0.68 | CRHR1 (0.38) | PTGS1PTGS2XDHCNR1TDP1 | |
| SCHEMBL12696493 | 0.68 | USP2 (0.33) | PTGS1PTGS2XDHBACE1SLC6A2 | |
| SCHEMBL19852570 | 0.67 | PTGS1 (0.40) | PTGS1PTGS2XDHALOX5BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203145-A1 | 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | ALOX5, LOX, ALOX15 | PTGS1 36/4885PTGS2 31/4885XDH 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.