SCHEMBL4797006

SCHEMBL4797006

C[n+]1ccc(C2=CC3=CC4=NC(=CC5=NC(=CC6=NC(=CC2=N3)C=C6)C=C5)C=C4)cc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PABPC1 P11940 1/20 0.33
▸ APOBEC3A P31941 1/20 0.33
▸ EIF4H Q15056 1/20 0.33
▸ APOBEC3G Q9HC16 1/20 0.33
▸ SLC22A2 O15244 1/20 0.32
▸ SLC22A1 O15245 1/20 0.32
▸ SLC22A3 O75751 1/20 0.32
▸ SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5319098 0.81 — —
SCHEMBL473159 0.81 MAOA (0.32) —
SCHEMBL3799009 0.81 — —
SCHEMBL5139611 0.75 — —
Hydrochloric Acid SCHEMBL16188273 0.72 BCL2L1 (0.33) —
SCHEMBL2942317 0.72 CYP1A1 (0.34) —
SCHEMBL2951402 0.71 PDE4A (0.36) APOBEC3G
Hydrochloric Acid SCHEMBL8585892 0.71 ENPP2 (0.33) —
SCHEMBL5576021 0.70 KDM4E (0.33) —
SCHEMBL5013668 0.70 ALDH1A1 (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006034009-A2 PURIFICATION OF BIOMOLECULES FROM CONTAMINATING INTACT NUCLEIC ACIDS SIGMA-ALDRICH CO. (US) 2006-03-30 — — WO claimed
US-20060068430-A1 Purification of biomolecules from contaminating intact nucleic acids SIGMA-ALDRICH CO. 2006-03-30 — — US claimed
CN-115996754-A Prophylactic and therapeutic immunotherapy of propionibacterium acnes 免疫之源生物技术有限公司 2023-04-21 — — CN disclosed
US-7445641-B1 Biomaterials modified with superoxide dismutase mimics PHARMACIA CORPORATION (US) 2008-11-04 — — US disclosed
US-20070179124-A1 Substituted Porphyrins FRIDOVICH IRWIN 2007-08-02 — — US disclosed
US-20060074062-A1 Substituted porphyrins DUKE UNIVERSITY (US) 2006-04-06 — — US disclosed
US-6916799-B2 Substituted porphyrins DUKE UNIVERSITY (US) 2005-07-12 — — US disclosed
WO-2005044149-A1 MODIFIED HYALURONIC ACID POLYMERS PHARMACIA CORPORATION (US) 2005-05-19 — — WO disclosed
EP-1185312-B1 BIOMATERIALS MODIFIED WITH SUPEROXIDE DISMUTASE MIMICS MONSANTO CO (US) 2005-03-23 — — EP disclosed
EP-1045851-B1 SUBSTITUTED PORPHYRINS UNIV DUKE (US) 2003-04-23 — — EP disclosed
EP-1185312-A2 BIOMATERIALS MODIFIED WITH SUPEROXIDE DISMUTASE MIMICS MONSANTO COMPANY (US) 2002-03-13 — — EP disclosed
US-20020022215-A1 Inactivation of small non-enveloped viruses and other microbial pathogens by porphyrins UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE 2002-02-21 — — US disclosed
WO-2002002153-A1 INACTIVATION OF PATHOGENS BY PORPHYRINS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2002-01-10 — — WO disclosed
EP-1045851-A4 SUBSTITUTED PORPHYRINS UNIV DUKE (US) 2001-05-09 — — EP disclosed
WO-2000072893-A2 BIOMATERIALS MODIFIED WITH SUPEROXIDE DISMUTASE MIMICS MONSANTO COMPANY (US) 2000-12-07 — — WO disclosed
EP-1045851-A1 SUBSTITUTED PORPHYRINS DUKE UNIVERSITY (US) 2000-10-25 — — EP disclosed
US-6087493-A ENZYME IHIBITORS REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-07-11 — — US disclosed
WO-1999023097-A1 SUBSTITUTED PORPHYRINS DUKE UNIVERSITY (US) 1999-05-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179124-A1 Substituted Porphyrins PPOX, GPX4, PRDX5 PABPC1 3022/4885APOBEC3A 2352/4885EIF4H 3075/4885
US-20060074062-A1 Substituted porphyrins PPOX, GPX4, PRDX5 PABPC1 3022/4885APOBEC3A 2352/4885EIF4H 3075/4885
US-20020022215-A1 Inactivation of small non-enveloped viruses and other microbial pathogens by porphyrins HMBS, PPOX, CD74 PABPC1 1575/4885APOBEC3A 241/4885EIF4H 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback