Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367812 | 0.78 | RAPGEF4 (0.51) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL2068967 | 0.77 | KMT2A (0.53) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL9818407 | 0.77 | GAA (0.56) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL3653050 | 0.74 | GAA (0.52) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL2004711 | 0.73 | HTR6 (0.71) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL9722812 | 0.72 | CA2 (0.57) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL8059962 | 0.72 | GAA (0.60) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL29204880 | 0.71 | GAA (0.48) | GAAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL17774540 | 0.71 | GAA (0.50) | GAARAPGEF4KMT2AKDM4EALDH1A1 | |
| SCHEMBL9299326 | 0.71 | ALDH1A1 (0.51) | GAARAPGEF4KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | claimed |
| US-20080312404-A1 | Novel diepoxides and epoxy resins | PEWS R GARTH | 2008-12-18 | — | — | US | disclosed |
| US-7462728-B2 | Diepoxide derivatives of N,N*-disubstituted disulfonamides | PEWS R GARTH | 2008-12-09 | — | — | US | disclosed |
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |