Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 9/20 | 0.51 |
| ▸ | CA1 | P00915 | 7/20 | 0.51 |
| ▸ | CA9 | Q16790 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976129 | 0.84 | PKM (0.71) | PKMESR1CA2CA1CA9 | |
| SCHEMBL193716 | 0.78 | LMNA (1.00) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL9839080 | 0.78 | LMNA (0.82) | LMNAPKMCA2CA1CA9 | |
| SCHEMBL28228467 | 0.76 | LMNA (0.96) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL3154840 | 0.76 | LMNA (0.88) | LMNACA2CA1CA9MEN1 | |
| SCHEMBL4506268 | 0.75 | CA1 (0.44) | LMNAPKMESR1CA2CA1 | |
| SCHEMBL4799669 | 0.74 | ALDH1A1 (0.69) | LMNAPKMESR1MEN1KMT2A | |
| SCHEMBL812682 | 0.73 | PKM (0.79) | LMNAPKMESR1CA2CA1 | |
| SCHEMBL4494785 | 0.73 | ESR1 (0.49) | LMNAPKMESR1CA2CA1 | |
| Methanesulfonamide SCHEMBL11803937 | 0.73 | LMNA (0.88) | LMNACA2CA1CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | claimed |
| US-20080312404-A1 | Novel diepoxides and epoxy resins | PEWS R GARTH | 2008-12-18 | — | — | US | disclosed |
| US-7462728-B2 | Diepoxide derivatives of N,N*-disubstituted disulfonamides | PEWS R GARTH | 2008-12-09 | — | — | US | disclosed |
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |