Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 11/20 | 0.58 |
| ▸ | CA9 | Q16790 | 11/20 | 0.58 |
| ▸ | CA1 | P00915 | 10/20 | 0.58 |
| ▸ | CA12 | O43570 | 9/20 | 0.58 |
| ▸ | CA7 | P43166 | 5/20 | 0.58 |
| ▸ | CA5A | P35218 | 4/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.58 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CA6 | P23280 | 2/20 | 0.58 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812682 | 0.85 | PKM (0.79) | PKMESR1CA2CA9CA1 | |
| SCHEMBL4801783 | 0.84 | LMNA (0.62) | PKMESR1CA2CA9CA1 | |
| SCHEMBL2114599 | 0.80 | ESR1 (1.00) | PKMESR1CA9CA12ALDH1A1 | |
| SCHEMBL3697451 | 0.80 | PKM (0.71) | PKMESR1CA9CA12ALDH1A1 | |
| SCHEMBL27561835 | 0.78 | CA2 (0.60) | CA2CA9CA1CA12CA7 | |
| SCHEMBL8154496 | 0.76 | PKM (0.50) | PKMESR1CA2CA9CA1 | |
| SCHEMBL6678557 | 0.76 | PKM (0.66) | PKMESR1CA9CA12ALDH1A1 | |
| SCHEMBL28263218 | 0.76 | CA2 (0.58) | CA2CA9CA1CA12CA7 | |
| SCHEMBL21745763 | 0.76 | PKM (0.65) | PKMESR1CA9CA12ALDH1A1 | |
| SCHEMBL21746060 | 0.76 | PKM (0.65) | PKMESR1CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589939-B1 | HYDROXY-FUNCTIONAL POLY(ETHER SULFONAMIDES) AS THERMOPLASTIC BARRIER RESINS | DOW CHEMICAL CO (US) | 1996-03-27 | — | — | EP | disclosed |