Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814435 | 0.89 | FFAR1 (0.60) | FFAR1FFAR4FAAHTRPV1F7 | |
| SCHEMBL28532074 | 0.89 | FFAR1 (0.65) | FFAR1FFAR4FAAHTRPV1F7 | |
| SCHEMBL4819792 | 0.89 | FFAR1 (0.56) | FFAR1FFAR4FAAHTRPV1MAPT | |
| SCHEMBL11429837 | 0.89 | FFAR1 (0.65) | FFAR1FFAR4FAAHTRPV1F7 | |
| SCHEMBL17249962 | 0.88 | ALDH1A1 (0.46) | FFAR1FFAR4TRPV1ALDH1A1F7 | |
| SCHEMBL19115282 | 0.86 | FFAR1 (0.60) | FFAR1FFAR4FAAHTRPV1F7 | |
| SCHEMBL4813908 | 0.86 | FFAR1 (0.60) | FFAR1FFAR4FAAHTRPV1F7 | |
| SCHEMBL19816447 | 0.81 | FFAR1 (0.41) | FFAR1FFAR4FAAHTRPV1ALDH1A1 | |
| SCHEMBL19816719 | 0.81 | FFAR1 (0.41) | FFAR1FFAR4FAAHTRPV1ALDH1A1 | |
| SCHEMBL17249969 | 0.80 | ALDH1A1 (0.44) | FFAR1FFAR4TRPV1ALDH1A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371779-B2 | Synergistic compositions of N-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENSE SCIENCE AND TECHNOLOGY (GB) | 2008-05-13 | — | — | US | claimed |
| US-20050014751-A1 | Use of n-acyl homoserine lactones for the treatment of insulitis | THE UNIVERSITY OF NOTTINGHAM (GB) | 2005-01-20 | — | — | US | claimed |
| US-20040259942-A1 | Modulation of stat activity | SHAW PETER (GB) | 2004-12-23 | — | — | US | claimed |
| EP-1404315-B1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | UNIV NOTTINGHAM (GB) | 2004-11-03 | — | — | EP | claimed |
| US-20040198978-A1 | Synergistic compositions of n-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2004-10-07 | — | — | US | claimed |
| EP-1425274-A1 | USE OF N-ACYL HOMOSERINE LACTONES FOR THE TREATMENT OF INSULITIS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2004-06-09 | — | — | EP | claimed |
| EP-1404315-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2004-04-07 | — | — | EP | claimed |
| US-20030171371-A1 | Immunosuppressant n-acyles homoserine lactones | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-09-11 | — | — | US | claimed |
| WO-2003022828-A1 | USE OF N-ACYL HOMOSERINE LACTONES FOR THE TREATMENT OF INSULITIS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-03-20 | — | — | WO | claimed |
| WO-2003004017-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-01-16 | — | — | WO | claimed |
| EP-1268459-A1 | IMMUNOSUPPRESSANT N-ACYL HOMOSERINE LACTONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-01-02 | — | — | EP | claimed |
| WO-2001074801-A1 | IMMUNOSUPPRESSANT N-ACYLES HOMOSERINE LACTONES | UNIVERSITY OF NOTTINGHAM (GB) | 2001-10-11 | — | — | WO | claimed |
| US-7371779-B2 | Synergistic compositions of N-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENSE SCIENCE AND TECHNOLOGY (GB) | 2008-05-13 | — | — | US | disclosed |
| US-20050014751-A1 | Use of n-acyl homoserine lactones for the treatment of insulitis | THE UNIVERSITY OF NOTTINGHAM (GB) | 2005-01-20 | — | — | US | disclosed |
| US-20040259942-A1 | Modulation of stat activity | SHAW PETER (GB) | 2004-12-23 | — | — | US | disclosed |
| EP-1404315-B1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | UNIV NOTTINGHAM (GB) | 2004-11-03 | — | — | EP | disclosed |
| US-20030171371-A1 | Immunosuppressant n-acyles homoserine lactones | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-09-11 | — | — | US | disclosed |
| WO-2003026641-A2 | MODULATION OF STAT ACTIVITY | UNIVERSITY OF NOTTINGHAM (GB) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003022828-A1 | USE OF N-ACYL HOMOSERINE LACTONES FOR THE TREATMENT OF INSULITIS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003004017-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259942-A1 | Modulation of stat activity | STAT3, STAT1, STAT4 | FFAR1 327/4885FFAR4 501/4885FAAH 2550/4885 |
| US-20050014751-A1 | Use of n-acyl homoserine lactones for the treatment of insulitis | HPGDS, CD14, IFNG | FFAR1 544/4885FFAR4 826/4885FAAH 299/4885 |
| US-20030171371-A1 | Immunosuppressant n-acyles homoserine lactones | MSR1, IL4, SRR | FFAR1 17/4885FFAR4 8/4885FAAH 358/4885 |
| US-20040198978-A1 | Synergistic compositions of n-acylhomoserine lactones and 4-quinolones | CBR3, CBR1, CNR1 | FFAR1 178/4885FFAR4 45/4885FAAH 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.