SCHEMBL481124

SCHEMBL481124

CC1C(=O)c2ccccc2C1(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
S100A4 P26447 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
PGR P06401 1/20 0.36
PDK2 Q15119 1/20 0.35
PDK4 Q16654 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 4/20 0.35
TP53 P04637 2/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
MAOA P21397 1/20 0.35
PTGS2 P35354 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GSK3B P49841 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20165763 1.00 ACHE (0.38) ACHES100A4MEN1KMT2APOLB
SCHEMBL29364950 1.00 ACHE (0.38) ACHES100A4MEN1KMT2APOLB
SCHEMBL30754346 1.00 ACHE (0.38) ACHES100A4MEN1KMT2APOLB
SCHEMBL17703888 0.80 ALDH1A1 (0.41) ACHES100A4MEN1KMT2APGR
SCHEMBL5327165 0.78 S100A4 (0.38) S100A4MEN1KMT2APOLBPGR
SCHEMBL11266220 0.75 ACHE (0.43) ACHEPOLBPGRPDK2MAPT
SCHEMBL3368766 0.75 MEN1 (0.35) S100A4MEN1KMT2APOLBPGR
SCHEMBL19303438 0.73 ACHE (0.34) ACHES100A4MEN1KMT2APOLB
SCHEMBL13880070 0.73 PDK2 (0.43) PDK2PDK4ALDH1A1MAPTHPGD
SCHEMBL14510715 0.71 ALDH1A1 (0.32) S100A4MEN1KMT2APOLBPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655373-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2025-12-03 EP claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
EP-4514477-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE Firmenich SA (CH) 2025-03-05 EP claimed
EP-4473079-A1 A FRAGRANCE MIXTURE Symrise AG (DE) 2024-12-11 EP claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
EP-4446001-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2024-10-16 EP claimed
US-20240301331-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-09-12 US claimed
WO-2024156688-A1 BIODEGRADABLE PERFUME COMPOSITION GIVAUDAN SA (CH) 2024-08-02 WO claimed
EP-4407019-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2024-07-31 EP claimed
EP-2046147-B1 METHOD OF USING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2013-05-01 EP claimed
WO-2013029958-A1 OUD ODORANTS FIRMENICH SA (CH) 2013-03-07 WO claimed
WO-2012085287-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2012-06-28 WO claimed
EP-1478616-B1 INDANES AND INDANONES AND THEIR USE IN PERFUMERY GIVAUDAN SA (CH) 2010-09-22 EP claimed
US-20090311403-A1 Method of Using Organic Compounds GIVAUDAN SA (CH) 2009-12-17 US claimed
CN-101494999-A Method for using organic compound GIVAUDAN SA (CH) 2009-07-29 CN claimed
US-20050148493-A1 Indanes and indanones and their use in perfumery FLACHSMANN FELIX (CH) 2005-07-07 US claimed
EP-1478616-A1 INDANES AND INDANONES AND THEIR USE IN PERFUMERY Givaudan SA (CH) 2004-11-24 EP claimed
WO-2003072533-A1 INDANES AND INDANONES AND THEIR USE IN PERFUMERY GIVAUDAN SA (CH) 2003-09-04 WO claimed
EP-1340741-A1 Indane derivatives and their use in perfumery Givaudan SA (CH) 2003-09-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090311403-A1 Method of Using Organic Compounds MGLL, GK, LIPC ACHE 817/4885S100A4 4097/4885MEN1 1073/4885
US-20050148493-A1 Indanes and indanones and their use in perfumery NISCH, CYP1B1, CYP2E1 ACHE 295/4885S100A4 1233/4885MEN1 4624/4885
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 ACHE 1315/4885S100A4 1722/4885MEN1 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.