Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292108 | 0.87 | LMNA (0.39) | LMNACYP2D6KDM4EMAPTSPHK1 | |
| SCHEMBL11587478 | 0.79 | MAPT (0.46) | LMNACYP2D6KDM4EMAPTSPHK1 | |
| E968 SCHEMBL2835144 | 0.78 | CES2 (0.43) | LMNACYP2D6KDM4EMAPTSPHK1 | |
| SCHEMBL16858613 | 0.76 | CES2 (0.53) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL9056653 | 0.76 | CES2 (0.53) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL378473 | 0.76 | CES2 (0.53) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL18339530 | 0.76 | CES2 (0.53) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL14777584 | 0.76 | CES2 (0.53) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL19357245 | 0.76 | CES2 (0.53) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL235095 | 0.76 | CES2 (0.53) | LMNAKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | GENFIT (FR) | 2006-07-13 | — | — | US | claimed |
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | claimed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | claimed |
| US-7375135-B2 | Fatty acid derivatives; preparation and uses thereof | GENFIT (FR) | 2008-05-20 | — | — | US | disclosed |
| EP-1673338-B1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-09-19 | — | — | EP | disclosed |
| US-20060252827-A1 | Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof | GENFIT (FR) | 2006-11-09 | — | — | US | disclosed |
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | GENFIT (FR) | 2006-07-13 | — | — | US | disclosed |
| EP-1673338-A1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | Genfit (FR) | 2006-06-28 | — | — | EP | disclosed |
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | disclosed |
| EP-1587508-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | Genfit (FR) | 2005-10-26 | — | — | EP | disclosed |
| US-20040192908-A1 | Fatty acid compounds, preparation and uses thereof | GENFIT (FR) | 2004-09-30 | — | — | US | disclosed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004069241-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | GENFIT (FR) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003014073-A1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | GENFIT (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252827-A1 | Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof | SGMS2, SGMS1, AGK | LMNA 4519/4885CYP2D6 4502/4885KDM4E 4174/4885 |
| US-20040192908-A1 | Fatty acid compounds, preparation and uses thereof | FASN, FFAR1, PLIN5 | LMNA 239/4885CYP2D6 3058/4885KDM4E 1096/4885 |
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | AGPAT5, HAGH, AGPAT2 | LMNA 4213/4885CYP2D6 3775/4885KDM4E 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.