Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811478 | 1.00 | CYP1A2 (0.53) | CYP1A2GRIA2VCAM1CYP3A4ALDH1A1 | |
| SCHEMBL2211091 | 0.90 | CYP1A2 (0.57) | CYP1A2GRIA2VCAM1CYP3A4ALDH1A1 | |
| SCHEMBL5631882 | 0.88 | CYP1A2 (0.58) | CYP1A2GRIA2VCAM1CYP3A4ALDH1A1 | |
| SCHEMBL19182411 | 0.85 | CYP1A2 (0.49) | CYP1A2GRIA2VCAM1CYP3A4ALDH1A1 | |
| SCHEMBL14809875 | 0.85 | CYP1A2 (0.49) | CYP1A2GRIA2ALDH1A1TSHRNPC1 | |
| SCHEMBL19180352 | 0.85 | CYP1A2 (0.49) | CYP1A2GRIA2VCAM1CYP3A4ALDH1A1 | |
| SCHEMBL10509942 | 0.85 | ALDH1A1 (0.44) | CYP1A2GRIA2VCAM1CYP3A4ALDH1A1 | |
| SCHEMBL4276693 | 0.82 | CYP1A2 (0.49) | CYP1A2GRIA2VCAM1CYP3A4ALDH1A1 | |
| SCHEMBL19180992 | 0.82 | RAB9A (0.46) | CYP1A2CYP3A4ALDH1A1NPC1RAB9A | |
| SCHEMBL19182419 | 0.81 | SIGMAR1 (0.47) | GRIA2VCAM1CYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345179-B2 | Process for producing pyrrolidine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20070105935-A1 | Process for producing pyrrolidine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1623975-A1 | PROCESS FOR PRODUCING PYRROLIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105935-A1 | Process for producing pyrrolidine derivative | ACSL4, ALDH18A1, LTA | CYP1A2 223/4885GRIA2 1772/4885VCAM1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.