SCHEMBL4815552

SCHEMBL4815552

CC[SiH](CC)OCCCN

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 1/20 0.39
DNM1 Q05193 8/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.33
CYP3A4 P08684 1/20 0.32
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820999 0.92 DNM1 (0.38) ODC1DNM1MEN1KMT2AALDH1A1
SCHEMBL3820966 0.90 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL4813006 0.83
SCHEMBL863615 0.78 ADRB2 (0.41) ALDH1A1TSHRCYP3A4
SCHEMBL9854576 0.76 THRB (0.37) MEN1KMT2ATSHR
SCHEMBL30366274 0.74 ALDH1A1 (0.30) ALDH1A1
SCHEMBL2389991 0.72
SCHEMBL3047759 0.72 CYP3A4 (0.37) ODC1DNM1MEN1KMT2AALDH1A1
SCHEMBL30366225 0.72 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL9069919 0.72 ODC1 (0.38) ODC1DNM1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7387832-B2 Flat particles and process for production thereof NISSHINBO INDUSTRIES, INC. (JP) 2008-06-17 US disclosed
US-7258921-B2 Composite particle with a carbodiimide resin layer and a process for producing the same NISSHINBO INDUSTRIES, INC. (JP) 2007-08-21 US disclosed
US-20060052549-A1 Flat particles and process for production thereof NISSHINBO INDUSTRIES, INC. (JP) 2006-03-09 US disclosed
US-20050271875-A1 Composite particle with a carbodimide resin layer and process for producing the same NISSHINBO INDUSTRIES, INC. (JP) 2005-12-08 US disclosed
EP-1553124-A1 FLAKY PARTICLES AND PROCESS FOR PRODUCTION THEREOF Nisshinbo Industries, Inc. (JP) 2005-07-13 EP disclosed
US-20050118424-A1 particles comprising thermoplastic resins impregnated with carbodiimide compounds, having heat and solvent resistance, used as curing agents, stabilizers, hardeners, adhesives, coatings, paints, reinforcements and in automobiles, electronics, furniture, construction materials and as spacers TAKAHASHI IKUO (JP) 2005-06-02 US disclosed
EP-1528077-A1 COMPOSITE PARTICLE HAVING CARBODIIMIDE RESIN LAYER AND PROCESS FOR PRODUCING THE SAME Nisshinbo Industries, Inc. (JP) 2005-05-04 EP disclosed
US-6866934-B2 A thermoplastic resin having a functional group and carbodiimide compound impregnated only in the surface layer section or both surface layer section and inside the base particle and both are strongly bonded by crosslinking reaction NISSHINBO INDUSTRIES, INC. (JP) 2005-03-15 US disclosed
US-20030215636-A1 A thermoplastic resin having a functional group and carbodiimide compound impregnated only in the surface layer section or both surface layer section and inside the base particle and both are strongly bonded by crosslinking reaction NISSHINBO INDUSTRIES, INC. (JP) 2003-11-20 US disclosed
EP-1344795-A2 Carbodiimide-containing hardening type reactive particles, process for producing the same, and use of the same NISSHINBO INDUSTRIES, INC. (JP) 2003-09-17 EP disclosed