Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198394 | 0.84 | CA1 (0.49) | RAB9ACA1CA2SUMO3SUMO2 | |
| SCHEMBL4822475 | 0.80 | RAB9A (0.50) | RAB9ACA1CA2SUMO3SUMO2 | |
| SCHEMBL3180002 | 0.74 | RAB9A (0.51) | RAB9ACA1CA2SUMO3SUMO2 | |
| SCHEMBL3322445 | 0.73 | CA1 (0.46) | RAB9ACA1CA2ALDH1A1MAPT | |
| SCHEMBL3188045 | 0.73 | CA1 (0.46) | RAB9ACA1CA2ALDH1A1MAPT | |
| SCHEMBL5184849 | 0.73 | RAB9A (0.56) | RAB9ASUMO3SUMO2SUMO1ALDH1A1 | |
| SCHEMBL16000121 | 0.71 | ALDH1A1 (0.69) | RAB9ASUMO3SUMO2SUMO1ALDH1A1 | |
| SCHEMBL10002559 | 0.71 | ADAMTS4 (0.56) | CA1CA2ALDH1A1 | |
| SCHEMBL4827852 | 0.71 | SLC1A3 (0.46) | — | |
| SCHEMBL3177957 | 0.71 | VCAM1 (0.58) | CA1CA2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323596-B2 | Antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH( .dbd. O) or of formula C( .dbd. O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of | DE NOVO PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| US-7323596-B2 | Antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH( .dbd. O) or of formula C( .dbd. O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of | DE NOVO PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| US-7323596-B2 | Antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH( .dbd. O) or of formula C( .dbd. O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of | DE NOVO PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| US-20040102491-A1 | Antimicrobial agents | DE NOVO PHARMACEUTICALS LTD. (GB) | 2004-05-27 | — | — | US | disclosed |
| EP-1343753-A2 | ANTIMICROBIAL AGENTS | De Novo Pharmaceuticals Ltd. (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050081-A2 | ANTIMICROBIAL AGENTS | DE NOVO PHARMACEUTICALS LTD (GB) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102491-A1 | Antimicrobial agents | CBR1, CYC1, MRM1 | RAB9A 2752/4885CA1 1948/4885CA2 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.