Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | ADA | P00813 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845252 | 0.85 | ESR1 (0.50) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| Ammonia Solution, Strong SCHEMBL11816347 | 0.83 | ESR1 (0.49) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL11816697 | 0.81 | SLC6A2 (0.58) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL7907492 | 0.81 | NQO2 (0.50) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL2480671 | 0.81 | KMT2A (0.51) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL4817621 | 0.81 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL5252569 | 0.80 | TDP1 (0.46) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL9859583 | 0.79 | SIGMAR1 (0.48) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL6754477 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 | |
| SCHEMBL11808889 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2C19CYP2D6SIGMAR1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358396-B2 | Preparation of optically active amines | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20070155971-A1 | Chiral diphosphorus compounds and their transition metal complexes | Source Global, PBC | 2007-07-05 | — | — | US | disclosed |
| US-7193092-B2 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| US-7078226-B1 | Method for producing optically active amines | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-18 | — | — | US | disclosed |
| US-20060122429-A1 | Preparation of optically active amines | DITRICH KLAUS | 2006-06-08 | — | — | US | disclosed |
| EP-1400527-B1 | Chiral diphosphorus compounds and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| EP-1398319-B1 | Chiral monophosphorus compounds and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-09 | — | — | EP | disclosed |
| CN-1204262-C | Method for producing optically active amines | BASF AG (DE) | 2005-06-01 | — | — | CN | disclosed |
| US-20050080047-A1 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-14 | — | — | US | disclosed |
| CN-1195764-C | Transition metal complex, preparation method and use thereof | BASF AG (DE) | 2005-04-06 | — | — | CN | disclosed |
| CN-1330074-A | Transition metal complex, preparation method and use thereof | BASF AG (DE) | 2002-01-09 | — | — | CN | disclosed |
| CN-1072227-C | Optically active diphosphine ligands | BASF AG (DE) | 2001-10-03 | — | — | CN | disclosed |
| EP-0906324-B1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AG (DE) | 2001-08-01 | — | — | EP | disclosed |
| US-6242583-B1 | COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | disclosed |
| WO-2001038292-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-31 | — | — | WO | disclosed |
| US-5990320-A | Optically active diphosphine ligands | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| CN-1219937-A | Carbohydrate derivatives and their solid-phase synthesis | BASF AG (DE) | 1999-06-16 | — | — | CN | disclosed |
| EP-0906324-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| CN-1202492-A | Optically active diphosphine ligands | BASF AG (DE) | 1998-12-23 | — | — | CN | disclosed |
| WO-1997045436-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122429-A1 | Preparation of optically active amines | MAOA, MAOB, NAAA | CYP1A2 165/4885CYP2C19 269/4885CYP2D6 616/4885 |
| US-20070155971-A1 | Chiral diphosphorus compounds and their transition metal complexes | CDIPT, DCPS, PIN1 | CYP1A2 1320/4885CYP2C19 1457/4885CYP2D6 201/4885 |
| US-20050080047-A1 | Chiral diphosphorus compounds and their transition metal complexes | CDIPT, DCPS, PIN1 | CYP1A2 1320/4885CYP2C19 1457/4885CYP2D6 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.