SCHEMBL482042

SCHEMBL482042

O=C(O)[C@H]1CC[C@H](O)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
LMNA P02545 2/20 0.50
PLG P00747 1/20 0.50
PLAT P00750 1/20 0.50
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50
GABRA5 P31644 1/20 0.50
GABRA3 P34903 1/20 0.50
GABRA2 P47869 1/20 0.50
GABRB2 P47870 1/20 0.50
GABRA4 P48169 1/20 0.50
GABRE P78334 1/20 0.50
PMP22 Q01453 1/20 0.50
GABRA6 Q16445 1/20 0.50
GABRG1 Q8N1C3 1/20 0.50
GABRG3 Q99928 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160291 1.00 TSHR (0.50) TSHRLMNAPLGPLATGABRP
SCHEMBL28889340 1.00 TSHR (0.50) TSHRLMNAPLGPLATGABRP
SCHEMBL601356 1.00 TSHR (0.50) TSHRLMNAPLGPLATGABRP
Ammonia Solution, Strong SCHEMBL27806834 0.97 LMNA (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL11415493 0.92 LMNA (0.44) TSHRLMNAPLGPLATGABRP
SCHEMBL28721496 0.90 TSHR (0.58) TSHRLMNAPLGPLATGABRP
SCHEMBL10949703 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL10956192 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL10959207 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL10956388 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 646 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115804739-B Qiu Jili fermented product, method for producing same, and use thereof 百岳特生物技术(上海)有限公司 2025-03-14 CN claimed
CN-115804739-A Fermented product of autumn plum, and its preparation method and application 百岳特生物技术(上海)有限公司 2023-03-17 CN claimed
CN-115433928-B Chemical silver plating liquid medicine and chemical silver plating method for 5G high-frequency circuit board 深圳市板明科技股份有限公司 2023-02-10 CN claimed
CN-115433928-A Chemical silver plating liquid medicine and chemical silver plating method for 5G high-frequency circuit board 深圳市板明科技股份有限公司 2022-12-06 CN claimed
CN-115224271-A Method for in-situ construction of zinc cathode artificial interface layer by simple soaking method 南通大学 2022-10-21 CN claimed
CN-114350428-B Antirust butterfly valve casting and machining method thereof 温州市海格阀门有限公司 2022-09-30 CN claimed
CN-114887636-A Mesoporous adjustable large-specific-surface-area oxide solid acid catalyst and preparation method and application thereof 内蒙古工业大学 2022-08-12 CN claimed
CN-114350428-A Antirust butterfly valve casting and machining method thereof 温州市海格阀门有限公司 2022-04-15 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
CN-212806242-U Vacuum drying oven for drying trans-4-hydroxycyclohexanecarboxylic acid 泰州精英化成医药科技有限公司 2021-03-26 CN claimed
US-20180258100-A1 RAPAMYCIN ANALOGS SHOWING IMPROVED mTORC1 SPECIFICITY AEOVIAN PHARMACEUTICALS, INC. 2018-09-13 US claimed
CN-106316825-A Preparing method for trans- 4- hydroxycyclohexanecarboxylic acid 泰州精英化成医药科技有限公司 2017-01-11 CN claimed
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof LG CHEM, LTD. (KR) 2026-05-19 US disclosed
US-20260132137-A1 SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF HOFFMANN LA ROCHE INC (US) 2026-05-14 US disclosed
US-20260092069-A1 SUBSTITUTED INDAZOLES AS IRAK4 INHIBITORS ASTRAZENECA AB (SE) 2026-04-02 US disclosed
EP-4423075-B1 CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2026-03-25 EP disclosed
US-5037849-A For treatment of heart and circulatory diseases BOEHRINGER MANNHEIM GMBH (DE) 1991-08-06 US disclosed
EP-0402110-A1 Optical active compounds and liquid crystal compositions containing such compounds WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-12-12 EP disclosed
WO-1988009322-A1 CYCLOBUTANE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-12-01 WO disclosed
US-4013582-A Liquid crystal compounds and electro-optic devices incorporating them RCA CORPORATION (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092069-A1 SUBSTITUTED INDAZOLES AS IRAK4 INHIBITORS IRAK3, IRAK4, IRAK2 TSHR 1780/4885LMNA 1389/4885PLG 4554/4885
US-20180258100-A1 RAPAMYCIN ANALOGS SHOWING IMPROVED mTORC1 SPECIFICITY RICTOR, MTOR, EIF4EBP1 TSHR 3788/4885LMNA 4438/4885PLG 4795/4885
US-20260132137-A1 SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF YWHAQ, CCT8, CYP2C18 TSHR 1929/4885LMNA 268/4885PLG 3108/4885
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof DGAT2, DGAT1, SOAT2 TSHR 2229/4885LMNA 3574/4885PLG 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.