SCHEMBL601356

SCHEMBL601356

O=C(O)[C@H]1CC[C@@H](O)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
LMNA P02545 2/20 0.50
PLG P00747 1/20 0.50
PLAT P00750 1/20 0.50
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50
GABRA5 P31644 1/20 0.50
GABRA3 P34903 1/20 0.50
GABRA2 P47869 1/20 0.50
GABRB2 P47870 1/20 0.50
GABRA4 P48169 1/20 0.50
GABRE P78334 1/20 0.50
PMP22 Q01453 1/20 0.50
GABRA6 Q16445 1/20 0.50
GABRG1 Q8N1C3 1/20 0.50
GABRG3 Q99928 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160291 1.00 TSHR (0.50) TSHRLMNAPLGPLATGABRP
SCHEMBL482042 1.00 TSHR (0.50) TSHRLMNAPLGPLATGABRP
SCHEMBL28889340 1.00 TSHR (0.50) TSHRLMNAPLGPLATGABRP
Ammonia Solution, Strong SCHEMBL27806834 0.97 LMNA (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL11415493 0.92 LMNA (0.44) TSHRLMNAPLGPLATGABRP
SCHEMBL28721496 0.90 TSHR (0.58) TSHRLMNAPLGPLATGABRP
SCHEMBL10949703 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL10956192 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL10959207 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP
SCHEMBL10956388 0.87 TSHR (0.48) TSHRLMNAPLGPLATGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117147721-A Method for distinguishing fermented soybeans from fermented soybeans 中南林业科技大学 2023-12-01 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
US-10435383-B2 C-glycoside derivatives OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2019-10-08 US claimed
US-20180118703-A1 C-GLYCOSIDE DERIVATIVES OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2018-05-03 US claimed
WO-2016151989-A1 C-GLYCOSIDE DERIVATIVES OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2016-09-29 WO claimed
US-20090312327-A1 PYRROLIDINE DERIVATIVES AS NK2 RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2009-12-17 US claimed
CN-122095093-A RNAi agents for inhibiting expression of inhibin subunit beta E (INHBE), pharmaceutical compositions and methods of use 2026-05-26 CN disclosed
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof LG CHEM, LTD. (KR) 2026-05-19 US disclosed
US-12570625-B2 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof NOVARTIS AG (CH) 2026-03-10 US disclosed
EP-4103559-B1 HETEROCYCLIC PAD4 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2026-03-04 EP disclosed
US-20260049088-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO LTD (CN) 2026-02-19 US disclosed
EP-4688782-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF Danatlas Pharmaceuticals Co., Ltd. (CN) 2026-02-11 EP disclosed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP disclosed
US-6410541-B2 BENZO(5,6)CYCLOHEPTA(1,2-B)PYRIDINE DERIVATIVES ADMINISTERED AS ANTITUMOR AGENTS SCHERING CORPORATION 2002-06-25 US disclosed
US-20010007870-A1 Benzo(5,6)cyclohepta(1,2-b)pyridine derivatives administered as antitumor agents REMISZEWSKI STACY W (US) 2001-07-12 US disclosed
US-6211193-B1 BENZO(5,6)CYCLOHEPTA(1,2-B)PYRIDINE DERIVATIVES; ANTITUMOR AND ANTICARCINOGENIC AGENTS SCHERING CORPORATION 2001-04-03 US disclosed
CN-1286690-A Compounds useful for inhibition of farnesyl protein transferase SCHERING CORP (US) 2001-03-07 CN disclosed
EP-0993459-A1 COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE SCHERING CORPORATION (US) 2000-04-19 EP disclosed
WO-1998057955-A1 COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE SCHERING CORPORATION (US) 1998-12-23 WO disclosed
US-5411989-A Cardiovascular disorders BOEHRINGER MANNHEIM, GMBH (DE) 1995-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435383-B2 C-glycoside derivatives UGCG, FUT6, FUT5 TSHR 3975/4885LMNA 3491/4885PLG 2377/4885
US-12570625-B2 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof IKZF1, IKZF2, BCL6 TSHR 3099/4885LMNA 952/4885PLG 4684/4885
US-20090312327-A1 PYRROLIDINE DERIVATIVES AS NK2 RECEPTOR ANTAGONISTS TACR2, PRLHR, AVPR2 TSHR 64/4885LMNA 3612/4885PLG 1942/4885
US-20010007870-A1 Benzo(5,6)cyclohepta(1,2-b)pyridine derivatives administered as antitumor agents HCCS, FNTB, CBR1 TSHR 2691/4885LMNA 3055/4885PLG 4810/4885
US-20180118703-A1 C-GLYCOSIDE DERIVATIVES UGCG, FUT6, FUT5 TSHR 3975/4885LMNA 3491/4885PLG 2377/4885
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof DGAT2, DGAT1, SOAT2 TSHR 2229/4885LMNA 3574/4885PLG 3875/4885
US-20260049088-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF SRD5A2, CBR1, SRD5A1 TSHR 255/4885LMNA 1297/4885PLG 4719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.