Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860447 | 0.89 | CDH1 (0.38) | POLBMAP3K5SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6855338 | 0.86 | NPC1 (0.38) | POLBMAP3K5SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6860552 | 0.82 | NPC1 (0.47) | POLBMAP3K5SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6862479 | 0.82 | MAPT (0.35) | RAB9ANPC1LMNAALDH1A1HPGD | |
| SCHEMBL6860602 | 0.82 | DHODH (0.36) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL5668737 | 0.80 | ACSS2 (0.39) | ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL6860753 | 0.80 | NPC1 (0.39) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4814951 | 0.80 | TSHR (0.31) | — | |
| SCHEMBL7901461 | 0.79 | NPC1 (0.41) | POLBSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL12706079 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305297-A1 | BENZOTRIAZOLES CONTAINING ALPHA-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | claimed |
| US-6451887-B1 | Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-17 | — | — | US | claimed |
| WO-2002012205-A1 | BENZOTRIAZOLES CONTAINING α-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | claimed |
| US-7419513-B2 | Hindered amine light stabilizers (HALS); for thermoset/thermoplastic resins, photographic applications, pigmented/dyed polypropylene, polyamide/polyester fibers, and for white, dyed, dipped, unscented/scented candle wax against discoloration and fading | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-09-02 | — | — | US | disclosed |
| US-20050043543-A1 | Benzotriazole/HALS molecular combinations and compositions stabilized therewith | WOOD MERVIN G (US) | 2005-02-24 | — | — | US | disclosed |
| US-6846929-B2 | Benzotriazole/hals molecular combinations and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-25 | — | — | US | disclosed |
| US-6800676-B2 | ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-05 | — | — | US | disclosed |
| EP-1305297-A1 | BENZOTRIAZOLES CONTAINING ALPHA-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-20030074833-A1 | Benzotriazole/hals molecular combinations and compositions stabilized therewith | CIBA SPECIALTY CHEMCIALS CORP. | 2003-04-24 | — | — | US | disclosed |
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORP. | 2003-01-02 | — | — | US | disclosed |
| WO-2002079173-A1 | BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | disclosed |
| US-6451887-B1 | Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-17 | — | — | US | disclosed |
| WO-2002012205-A1 | BENZOTRIAZOLES CONTAINING α-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030074833-A1 | Benzotriazole/hals molecular combinations and compositions stabilized therewith | TAS1R1, TAS1R2, BRWD1 | POLB 443/4885MAP3K5 4036/4885SMN1; SMN2 1462/4885 |
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | SUV39H1, SUV39H2, TPST2 | POLB 1012/4885MAP3K5 3898/4885SMN1; SMN2 2918/4885 |
| US-20050043543-A1 | Benzotriazole/HALS molecular combinations and compositions stabilized therewith | BRWD1, TAS1R2, TAS1R1 | POLB 351/4885MAP3K5 3854/4885SMN1; SMN2 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.