Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 2/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PPIG | Q13427 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26583577 | 0.85 | RAB9A (0.47) | ALDH1A1KDM4ECYP3A4LMNACA12 | |
| SCHEMBL4828246 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KDM4EHTTCYP3A4CYP1A2 | |
| SCHEMBL4828327 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTCYP3A4LMNA | |
| SCHEMBL6257260 | 0.79 | HIF1A (0.44) | ALDH1A1KDM4ECYP3A4LMNATSHR | |
| SCHEMBL6214399 | 0.78 | LMNA (0.49) | LMNASMN1; SMN2GAAPOLB | |
| SCHEMBL11708373 | 0.77 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL11725209 | 0.77 | L3MBTL1 (0.43) | ALDH1A1HTTTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL17943725 | 0.77 | PDK1 (0.41) | HTTLMNASMN1; SMN2GAAMAPT | |
| SCHEMBL4829862 | 0.77 | CA12 (0.48) | ALDH1A1KDM4EHTTCYP3A4LMNA | |
| SCHEMBL13728211 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | claimed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | claimed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | KRT18, CDC73, JUP | ALDH1A1 509/4885KDM4E 599/4885HTT 2868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.