Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12206192 | 0.85 | MEN1 (0.50) | ALDH1A1TDP1L3MBTL1LTA4HPKM | |
| SCHEMBL16020929 | 0.82 | KMT2A (0.52) | ALDH1A1PKMMEN1KMT2ASLC6A3 | |
| SCHEMBL13148615 | 0.82 | KMT2A (0.59) | PKMMEN1KMT2ASLC6A3GAA | |
| SCHEMBL10284918 | 0.82 | SMN1; SMN2 (0.55) | ALDH1A1PKMMEN1KMT2ASLC6A3 | |
| SCHEMBL5149718 | 0.81 | NOS1 (0.51) | TSHRCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2263697 | 0.81 | SLC6A3 (0.53) | ALDH1A1PKMMEN1KMT2ASLC6A3 | |
| SCHEMBL10284908 | 0.79 | LMNA (0.55) | CYP3A4ALDH1A1TDP1L3MBTL1LTA4H | |
| SCHEMBL13611430 | 0.79 | CYP17A1 (0.46) | CYP3A4LTA4HPKMMEN1KMT2A | |
| SCHEMBL4829173 | 0.79 | HDAC1 (0.44) | TSHRCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10284720 | 0.78 | LTA4H (0.49) | ALDH1A1LTA4HPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287438-A1 | Agent for preventing or treating neuropathy | MOMOSE YU | 2008-11-20 | — | — | US | disclosed |
| US-7423159-B2 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-09 | — | — | US | disclosed |
| CN-100334083-C | Piperidine derivatives as CCR5 inhibitors | NOVARTIS AG (CH) | 2007-08-29 | — | — | CN | disclosed |
| US-20060004069-A1 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
| CN-1703411-A | Piperidine derivatives as CCR5 inhibitors | NOVARTIS AG (CH) | 2005-11-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004069-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | TSHR 1173/4885CYP3A4 2152/4885ALDH1A1 2652/4885 |
| US-20080287438-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | TSHR 1173/4885CYP3A4 2152/4885ALDH1A1 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.