Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829313 | 1.00 | LMNA (0.41) | LMNAALDH1A1GAATBXAS1MAPT | |
| SCHEMBL7521545 | 0.88 | RAB9A (0.48) | LMNATBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL7521527 | 0.88 | RAB9A (0.48) | LMNATBXAS1MEN1KMT2ANPC1 | |
| SCHEMBL4836447 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL4834260 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1GAAMAPTMEN1 | |
| SCHEMBL4834245 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1GAAMAPTMEN1 | |
| SCHEMBL14109842 | 0.74 | TDP1 (0.43) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4834668 | 0.72 | MMP1 (0.41) | LMNAALDH1A1MAPTMEN1POLB | |
| SCHEMBL4834693 | 0.72 | MMP1 (0.41) | LMNAALDH1A1MAPTMEN1POLB | |
| SCHEMBL5591568 | 0.70 | TBXAS1 (0.43) | LMNAALDH1A1GAATBXAS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287438-A1 | Agent for preventing or treating neuropathy | MOMOSE YU | 2008-11-20 | — | — | US | disclosed |
| US-7423159-B2 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-09 | — | — | US | disclosed |
| US-20060004069-A1 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1539838-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.P.A. (IT) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024785-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004069-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | LMNA 2405/4885ALDH1A1 2652/4885GAA 4645/4885 |
| US-20080287438-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | LMNA 2405/4885ALDH1A1 2652/4885GAA 4645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.