Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4833254 | 0.99 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2PDK1PDK2 | |
| SCHEMBL24258886 | 0.89 | LMNA (0.47) | ALDH1A1MAPTSMN1; SMN2PDK1PDK2 | |
| SCHEMBL9779966 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2PDK1PDK2 | |
| SCHEMBL4030860 | 0.84 | LMNA (0.54) | ALDH1A1MAPTSMN1; SMN2PDK1PDK2 | |
| SCHEMBL4833044 | 0.82 | SMN1; SMN2 (0.50) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4833038 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| Water SCHEMBL27467718 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9468482 | 0.79 | MAPT (0.62) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27993807 | 0.79 | PDK1 (0.47) | ALDH1A1MAPTSMN1; SMN2PDK1PDK2 | |
| SCHEMBL10126717 | 0.78 | MTNR1B (0.67) | ALDH1A1SMN1; SMN2KMT2AGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | ALDH1A1 1819/4885MAPT 763/4885SMN1; SMN2 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.