Sugi Predict

Sugi Predict / Compounds / SCHEMBL483552

SCHEMBL483552

SCHEMBL483552

c1ccc(-c2cccc3oc4ccccc4c23)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 10/20 0.45
▸ ALDH1A1 P00352 6/20 0.45
▸ TP53 P04637 5/20 0.45
▸ SMN1; SMN2 Q16637 5/20 0.45
▸ HPGD P15428 5/20 0.45
▸ HSD17B10 Q99714 5/20 0.45
▸ NPC1 O15118 5/20 0.45
▸ RAB9A P51151 3/20 0.45
▸ CYP1A2 P05177 2/20 0.45
▸ CYP2C9 P11712 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ MAPT P10636 5/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ LMNA P02545 3/20 0.43
▸ CCR1 P32246 2/20 0.43
▸ CCR5 P51681 2/20 0.43
▸ CCR8 P51685 2/20 0.43
▸ POLB P06746 1/20 0.43
▸ METAP1 P53582 1/20 0.43
▸ BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30022079 1.00 KDM4E (0.45) KDM4EALDH1A1TP53SMN1; SMN2HPGD
Biphenyl SCHEMBL29177696 0.94 KDM4E (0.41) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL3708192 0.87 MAOA (0.51) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL21616062 0.84 NPC1 (0.48) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL28573310 0.84 KDM4E (0.38) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL28567091 0.84 KDM4E (0.38) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL483218 0.83 ALOX5 (0.50) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL29496934 0.83 ALOX5 (0.50) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL21019864 0.82 AHR (0.45) KDM4EALDH1A1TP53SMN1; SMN2HPGD
SCHEMBL25636957 0.82 KDM4E (0.39) KDM4EALDH1A1TP53SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 — — EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 — — US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 — — EP disclosed
EP-4311849-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-01-29 — — EP disclosed
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-05-30 — — US disclosed
US-20240059721-A1 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-22 — — US disclosed
US-11910701-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 — — US disclosed
EP-4311849-A1 METAL COMPLEXES UDC Ireland Limited (IE) 2024-01-31 — — EP disclosed
CN-117466945-A metal complex UDC爱尔兰有限公司 2024-01-30 — — CN disclosed
CN-117447526-A Containing fluorine-substituted metal complexes 北京夏禾科技有限公司 2024-01-26 — — CN disclosed
EP-2730583-A1 Iridium complexes with aza-benzo fused ligands Universal Display Corporation (US) 2014-05-14 — — EP disclosed
US-8722205-B2 Heteroleptic iridium complex UNIVERSAL DISPLAY CORPORATION (US) 2014-05-13 — — US disclosed
EP-2710020-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY Universal Display Corporation (US) 2014-03-26 — — EP disclosed
EP-2650941-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2013-10-16 — — EP disclosed
US-20130248845-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-09-26 — — US disclosed
US-20120292601-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY UNIVERSAL DISPLAY CORPORATION (US) 2012-11-22 — — US disclosed
WO-2012158851-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY UNIVERSAL DISPLAY CORPORATION (US) 2012-11-22 — — WO disclosed
EP-2411401-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2012-02-01 — — EP disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — US disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11910701-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 KDM4E 2475/4885ALDH1A1 721/4885TP53 2973/4885
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 KDM4E 2475/4885ALDH1A1 721/4885TP53 2973/4885
US-20120292601-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY POF1B, OCIAD1, OCIAD2 KDM4E 2307/4885ALDH1A1 4320/4885TP53 4289/4885
US-20240059721-A1 Metal complexes MCU, IMMT, SOD1 KDM4E 4540/4885ALDH1A1 1407/4885TP53 3817/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 KDM4E 3232/4885ALDH1A1 1085/4885TP53 3768/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 KDM4E 299/4885ALDH1A1 1179/4885TP53 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.