SCHEMBL26452

SCHEMBL26452

CC(C)(C)OB(O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 4/20 0.44
ENPP2 Q13822 4/20 0.44
ORAI1 Q96D31 3/20 0.44
ORAI2 Q96SN7 3/20 0.44
ORAI3 Q9BRQ5 3/20 0.44
PCSK9 Q8NBP7 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ALDH1A1 P00352 3/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPK1 P28482 1/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1507183 0.94 TRPV6 (0.39) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL25376692 0.84 TRPV6 (0.42) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL119711 0.81 TRPV6 (0.39) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL10057608 0.81 MGLL (0.44) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL8925345 0.80 ENPP2 (0.46) ENPP2CA4CA5ACA14CA5B
SCHEMBL5952636 0.79 TRPV6 (0.38) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL8515033 0.77 TRPV6 (0.44) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL483731 0.77 TRPV6 (0.45) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL26451 0.76 TRPV6 (0.40) TRPV6ENPP2ORAI1ORAI2ORAI3
SCHEMBL691860 0.73 ENPP2 (0.50) TRPV6ENPP2ORAI1ORAI2ORAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005471-A Novel method for synthesizing 4-tert-butyl biphenyl by using palladium to catalyze tetrafluorothianthrene salt 内蒙古大学 2024-05-10 CN claimed
CN-122010899-A Continuous flow preparation method of lenalidomide and derivatives thereof 深圳连续制药科技有限公司 2026-05-12 CN disclosed
US-12509480-B2 Organometallic complex, light emitting diode, and electronic device KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-12-30 US disclosed
US-12065560-B2 Propylene-ethylene random copolymer LG CHEM, LTD. (KR) 2024-08-20 US disclosed
CN-118005471-A Novel method for synthesizing 4-tert-butyl biphenyl by using palladium to catalyze tetrafluorothianthrene salt 内蒙古大学 2024-05-10 CN disclosed
CN-117247362-B Light conversion agent with asymmetric structure, light conversion adhesive film and preparation method thereof 常州百佳年代薄膜科技股份有限公司 2024-02-13 CN disclosed
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
CN-112513051-B Compound and color conversion film comprising the same 株式会社LG化学 2023-12-26 CN disclosed
CN-117247362-A Light conversion agent with asymmetric structure, light conversion adhesive film and preparation method thereof 常州百佳年代薄膜科技股份有限公司 2023-12-19 CN disclosed
EP-3936542-B1 PROPYLENE-ETHYLENE RANDOM COPOLYMER LG CHEMICAL LTD (KR) 2023-11-08 EP disclosed
US-6963017-B2 Preparation of preparing substituted indanones BASELL POLYOLEFINE GMBH (DE) 2005-11-08 US disclosed
EP-0968158-B1 METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM BASELL POLYOLEFINE GMBH (DE) 2005-08-10 EP disclosed
US-6916893-B2 Polymerization-active transition metal complexes having bulky ligand systems SER. V. GMBH (DE) 2005-07-12 US disclosed
WO-2005058916-A2 ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PREPARATION OF POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2005-06-30 WO disclosed
US-20050059705-A1 Aryl and heteroaryl compounds, compositions, and methods of use VTVX HOLDINGS I LLC 2005-03-17 US disclosed
WO-2005014533-A2 ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE TRANSTECH PHARMA, INC. (US) 2005-02-17 WO disclosed
US-20050033076-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2005-02-10 US disclosed
US-20040171774-A1 Polymerization-active transition metal complexes having bulky ligand systems RIEGER BERNHARD (DE) 2004-09-02 US disclosed
US-20030009046-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2003-01-09 US disclosed
EP-0832082-B1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ASTRAZENECA AB (SE) 2001-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059705-A1 Aryl and heteroaryl compounds, compositions, and methods of use TFPI, F3, F2 TRPV6 4377/4885ENPP2 71/4885ORAI1 4596/4885
US-12509480-B2 Organometallic complex, light emitting diode, and electronic device GRK1, CRY1, NR2E3 TRPV6 350/4885ENPP2 3768/4885ORAI1 1917/4885
US-11858952-B2 Compound and color conversion film comprising same BLVRB, CDYL, CRY1 TRPV6 4523/4885ENPP2 2784/4885ORAI1 4405/4885
US-20050033076-A1 Preparation of preparing substituted indanones CYP1A2, CYP2J2, IDH3A TRPV6 4172/4885ENPP2 4721/4885ORAI1 4605/4885
US-20030009046-A1 Preparation of preparing substituted indanones CYP1A2, CYP1B1, CYP1A1 TRPV6 4133/4885ENPP2 4773/4885ORAI1 4577/4885
US-20040171774-A1 Polymerization-active transition metal complexes having bulky ligand systems AP1M1, CCNC, CLTB TRPV6 2917/4885ENPP2 4276/4885ORAI1 2356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.