Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046288 | 0.91 | PARP1 (0.59) | PARP1ALDH1A1EGLN1POLBKDM4E | |
| SCHEMBL12020195 | 0.81 | ALDH1A1 (0.62) | PARP1L3MBTL1ALDH1A1EGLN1POLB | |
| Phenanthroline SCHEMBL6308806 | 0.78 | KDM4E (0.61) | PARP1L3MBTL1ALDH1A1EGLN1KDM4E | |
| SCHEMBL12020192 | 0.77 | KDM4E (0.55) | ALDH1A1EGLN1POLBKDM4EMEN1 | |
| Trifluoroacetic Acid SCHEMBL29810625 | 0.76 | RAB9A (0.49) | PARP1L3MBTL1ALDH1A1KDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL484379 | 0.76 | RAB9A (0.49) | PARP1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL2718494 | 0.71 | SLC40A1 (0.47) | ALDH1A1EGLN1KDM4E | |
| SCHEMBL2143721 | 0.70 | ALDH1A1 (0.73) | PARP1ALDH1A1EGLN1KDM4E | |
| SCHEMBL19358748 | 0.69 | ALDH1A1 (0.54) | PARP1L3MBTL1ALDH1A1EGLN1KDM4E | |
| Trifluoroacetic Acid SCHEMBL28713988 | 0.69 | LMNA (0.70) | PARP1L3MBTL1ALDH1A1EGLN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411376-A1 | INHIBITORS OF NF-KB | Profectus Biosciences, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |