Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839051 | 0.92 | CHEK2 (0.36) | ALDH1A1CHEK2HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL4842803 | 0.87 | KMT2A (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Trifluoroacetic Acid SCHEMBL4843563 | 0.85 | ALDH1A1 (0.41) | ALDH1A1CHEK2HPGDMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4843965 | 0.85 | DRD2 (0.39) | ALDH1A1CHEK2HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL4844131 | 0.84 | HDAC6 (0.39) | ALDH1A1CHEK2HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL4837229 | 0.84 | KDM4E (0.40) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL4840541 | 0.84 | HTR5A (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Trifluoroacetic Acid SCHEMBL4840737 | 0.83 | HDAC6 (0.44) | CHEK2HDAC3HDAC4HDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL4842215 | 0.83 | HDAC6 (0.41) | CHEK2HDAC6MEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL4837280 | 0.83 | CDK4 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | ALDH1A1 1489/4885CHEK2 309/4885HDAC3 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.