Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260119 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTGAATDP1 | |
| Trifluoroacetic Acid SCHEMBL4839496 | 0.86 | LDHA (0.38) | ALDH1A1MAPTGAARAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL4844112 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTCHEK2SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4843358 | 0.84 | ABL1 (0.44) | ALDH1A1KDM4EMAPTTDP1CHEK2 | |
| Trifluoroacetic Acid SCHEMBL4842251 | 0.84 | TPH1 (0.37) | L3MBTL1HPGDMMP2MMP9MMP8 | |
| Trifluoroacetic Acid SCHEMBL5259763 | 0.84 | MMP2 (0.35) | ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4843652 | 0.82 | FFAR1 (0.42) | MAPTRAB9ASMN1; SMN2NPC1TP53 | |
| Trifluoroacetic Acid SCHEMBL4845670 | 0.82 | FFAR1 (0.42) | CHEK2 | |
| Trifluoroacetic Acid SCHEMBL4844286 | 0.81 | LDHA (0.35) | RAB9ANPC1TP53KMT2AMMP2 | |
| Trifluoroacetic Acid SCHEMBL4839090 | 0.81 | GPR6 (0.43) | L3MBTL1CNR2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | ALDH1A1 1489/4885KDM4E 2903/4885MAPT 3669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.