Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 4/20 | 0.31 |
| ▸ | MMP9 | P14780 | 4/20 | 0.31 |
| ▸ | MMP8 | P22894 | 4/20 | 0.31 |
| ▸ | MMP13 | P45452 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261588 | 0.94 | LDHA (0.36) | LDHALDHBPTGS2HAO1HPSE | |
| Trifluoroacetic Acid SCHEMBL4839496 | 0.88 | LDHA (0.38) | LDHALDHBPTGS2HAO1HPSE | |
| Trifluoroacetic Acid SCHEMBL4843563 | 0.81 | ALDH1A1 (0.41) | PTGS2TP53MMP2MMP9MMP8 | |
| SCHEMBL5257434 | 0.80 | NPC1 (0.39) | LDHALDHBPTGS2HAO1HPSE | |
| Trifluoroacetic Acid SCHEMBL5259763 | 0.80 | MMP2 (0.35) | HPSEMMP2MMP9MMP8MMP13 | |
| Trifluoroacetic Acid SCHEMBL4837278 | 0.79 | HPSE (0.45) | HPSENPC1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL4844134 | 0.79 | HPSE (0.36) | HPSEMMP2MMP9MMP8MMP13 | |
| Trifluoroacetic Acid SCHEMBL4846619 | 0.79 | MMP2 (0.35) | HPSESIRT2TP53MMP2MMP9 | |
| SCHEMBL27614959 | 0.78 | HPSE (0.36) | LDHALDHBPTGS2HAO1HPSE | |
| Trifluoroacetic Acid SCHEMBL4843358 | 0.78 | ABL1 (0.44) | PTGS2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | LDHA 2904/4885LDHB 3184/4885PTGS2 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.