Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256810 | 0.91 | ABL1 (0.44) | ABL1SRCSMN1; SMN2MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL5259763 | 0.89 | MMP2 (0.35) | ABL1SRCSMN1; SMN2MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL4838956 | 0.86 | SCD (0.42) | SMN1; SMN2MAPTALDH1A1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL4843965 | 0.85 | DRD2 (0.39) | ABL1SRCSMN1; SMN2MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL4843563 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4844349 | 0.84 | HPSE (0.36) | NPC1PTGS2 | |
| Trifluoroacetic Acid SCHEMBL4834113 | 0.83 | MMP2 (0.36) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL4839496 | 0.82 | LDHA (0.38) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4843652 | 0.82 | FFAR1 (0.42) | ABL1SRCSMN1; SMN2MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL4842251 | 0.82 | TPH1 (0.37) | HPGDL3MBTL1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | ABL1 272/4885SRC 535/4885SMN1; SMN2 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.